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[HTML][HTML] Synthesis of ethyl pyrimidine-quinolincarboxylates selected from virtual screening as enhanced lactate dehydrogenase (LDH) inhibitors
The inhibition of the hLDHA (human lactate dehydrogenase A) enzyme has been
demonstrated to be of great importance in the treatment of cancer and other diseases, such …
demonstrated to be of great importance in the treatment of cancer and other diseases, such …
[HTML][HTML] Qualitative Profiling, Antioxidant and Antimicrobial Activities of Polar and Nonpolar Basil Extracts
V Vidaković, B Vujić, M Jadranin, I Novaković… - Foods, 2024 - mdpi.com
Basil (Ocimum basilicum L.) is a widely used culinary herb. In this study, ethanol,
dichloromethane, and sunflower oil were used separately as solvents with distinct polarities …
dichloromethane, and sunflower oil were used separately as solvents with distinct polarities …
Discovery of a new class of potent pyrrolo [3, 4-c] quinoline-1, 3-diones based inhibitors of human dihydroorotate dehydrogenase: Synthesis, pharmacological and …
Abstract Twenty N-substituted pyrrolo [3, 4-c] quinoline-1, 3-diones 3a-t were synthesized by
a cyclization reaction of Pfitzinger's quinoline ester precursor with the selected aromatic …
a cyclization reaction of Pfitzinger's quinoline ester precursor with the selected aromatic …
Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking
X Ren, X Liu, M Hua, Y Dai, X Ren… - Chemical Biology & …, 2024 - Wiley Online Library
Human dihydroorotate dehydrogenase (h DHODH) is a key enzyme that catalyzes the de
novo synthesis of pyrimidine. In recent years, various studies have shown that inhibiting this …
novo synthesis of pyrimidine. In recent years, various studies have shown that inhibiting this …