Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo
Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
Antimicrobial peptides: mechanisms of action and resistance
B Bechinger, SU Gorr - Journal of dental research, 2017 - journals.sagepub.com
More than 40 antimicrobial peptides and proteins (AMPs) are expressed in the oral cavity.
These AMPs have been organized into 6 functional groups, 1 of which, cationic AMPs, has …
These AMPs have been organized into 6 functional groups, 1 of which, cationic AMPs, has …
Mechanisms of action for antimicrobial peptides with antibacterial and antibiofilm functions
N Raheem, SK Straus - Frontiers in microbiology, 2019 - frontiersin.org
The antibiotic crisis has led to a pressing need for alternatives such as antimicrobial
peptides (AMPs). Recent work has shown that these molecules have great potential not only …
peptides (AMPs). Recent work has shown that these molecules have great potential not only …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
The chemistry and biological activities of peptides from amphibian skin secretions
X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …
environmental factors including microorganisms, parasites, predators, and physical factors …
Host defense peptides: Dual antimicrobial and immunomodulatory action
M Drayton, JP Deisinger, KC Ludwig… - International Journal of …, 2021 - mdpi.com
The rapid rise of multidrug-resistant (MDR) bacteria has once again caused bacterial
infections to become a global health concern. Antimicrobial peptides (AMPs), also known as …
infections to become a global health concern. Antimicrobial peptides (AMPs), also known as …
Tryptophan-and arginine-rich antimicrobial peptides: anti-infectives with great potential
SK Straus - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2024 - Elsevier
With the increasing prevalence of multidrug resistant (MDR) bacteria, there is a need to
design synthetic antimicrobial peptides (AMPs) that are effective and selective for bacteria …
design synthetic antimicrobial peptides (AMPs) that are effective and selective for bacteria …
Biophysical investigations elucidating the mechanisms of action of antimicrobial peptides and their synergism
A Marquette, B Bechinger - Biomolecules, 2018 - mdpi.com
Biophysical and structural investigations are presented with a focus on the membrane lipid
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …
The mechanisms of action of cationic antimicrobial peptides refined by novel concepts from biophysical investigations
C Aisenbrey, A Marquette, B Bechinger - Antimicrobial Peptides: Basics …, 2019 - Springer
Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …
how these peptides interact with membranes can still bear surprises and add new …
Model architectures for bacterial membranes
The complex composition of bacterial membranes has a significant impact on the
understanding of pathogen function and their development towards antibiotic resistance. In …
understanding of pathogen function and their development towards antibiotic resistance. In …