Migraine is a complex brain disorder explained by the interaction of genetic and
environmental factors. In monogenic migraines, including familial hemiplegic migraine and …

Background and Objectives Cluster headache and migraine have circadian features at
multiple levels (cellular, systems, and behavioral). A thorough understanding of their …

Objective The objective of this study was to aggregate data for the first genomewide
association study meta‐analysis of cluster headache, to identify genetic risk variants, and …

Cluster headache and migraine are regarded as distinct primary headaches. While cluster
headache and migraine differ in multiple aspects such as gender-related and headache …

Background Migraine is considered a multifactorial genetic disorder. Different platforms and
methods are used to unravel the genetic basis of migraine. Initially, linkage analysis in …

Background/Hypothesis Cluster headache displays uniquely rhythmic patterns in its attack
manifestation. This strong chronobiological influence suggests that part of the …

Background Cluster headache is a highly debilitating neurological disorder with
considerable inter-ethnic differences. Genome-wide association studies (GWAS) recently …

Objective This article reviews the epidemiology, clinical features, differential diagnosis,
pathophysiology, and management of three types of trigeminal autonomic cephalalgias …

Background and purpose The response to cluster headache treatments has a high
interindividual variation. To date, treatment response has only been assessed by a …

Background Chronic migraine, a highly disabling migraine subtype, affects nearly 2% of the
general population. Understanding migraine chronification is vital for develo** better …