NADPH oxidases (NOX): an overview from discovery, molecular mechanisms to physiology and pathology
The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …
identified in the membrane of phagocytic cells. For many years, its only known role was in …
NADPH oxidases: an overview from structure to innate immunity-associated pathologies
Oxygen-derived free radicals, collectively termed reactive oxygen species (ROS), play
important roles in immunity, cell growth, and cell signaling. In excess, however, ROS are …
important roles in immunity, cell growth, and cell signaling. In excess, however, ROS are …
Nox family NADPH oxidases: molecular mechanisms of activation
NADPH oxidases of the Nox family are important enzymatic sources of reactive oxygen
species (ROS). Numerous homologue-specific mechanisms control the activity of this …
species (ROS). Numerous homologue-specific mechanisms control the activity of this …
Hydrogen peroxide: a signaling messenger
JR Stone, S Yang - Antioxidants & redox signaling, 2006 - liebertpub.com
Hydrogen peroxide (H2O2) is a well-documented component of living cells. It plays
important roles in host defense and oxidative biosynthetic reactions. In addition there is …
important roles in host defense and oxidative biosynthetic reactions. In addition there is …
[BOOK][B] Oxidation and antioxidants in organic chemistry and biology
ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …
compounds and polymers, and biological processes mediated by free radicals, Oxidation …
Vascular NAD (P) H oxidases: specific features, expression, and regulation
B Lassegue, RE Clempus - American Journal of Physiology …, 2003 - journals.physiology.org
The importance of reactive oxygen species (ROS) in vascular physiology and pathology is
becoming increasingly evident. All cell types in the vascular wall produce ROS derived from …
becoming increasingly evident. All cell types in the vascular wall produce ROS derived from …
NADPH oxidases in vascular pathology
A Konior, A Schramm… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Reactive oxygen species (ROS) play a critical role in vascular disease. While
there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate …
there are many possible sources of ROS, nicotinamide adenine dinucleotide phosphate …
Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant
S Heumüller, S Wind, E Barbosa-Sicard… - …, 2008 - Am Heart Assoc
A large body of literature suggest that vascular reduced nicotinamide-adenine dinucleotide
phosphate (NADPH) oxidases are important sources of reactive oxygen species. Many …
phosphate (NADPH) oxidases are important sources of reactive oxygen species. Many …
Effect of reactive oxygen species on the endoplasmic reticulum and mitochondria during intracellular pathogen infection of mammalian cells
J Lee, CH Song - Antioxidants, 2021 - mdpi.com
Oxidative stress, particularly reactive oxygen species (ROS), are important for innate
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …
Oxidative stress: a major player in cerebrovascular alterations associated to neurodegenerative events
The brain is one of the most exquisite organs in the body with high metabolic demands, and
requires a tight regulation of the surrounding environment. This tight control is exerted by the …
requires a tight regulation of the surrounding environment. This tight control is exerted by the …