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Preparation and utility of organic pentafluorosulfanyl-containing compounds
PR Savoie, JT Welch - Chemical reviews, 2015 - ACS Publications
The organic chemistry of the pentafluorosulfanyl (SF5) group, previously reviewed 1 and
extensively developed by Gard, has only recently come under more widespread …
extensively developed by Gard, has only recently come under more widespread …
(Hetero)aryl‐SVI Fluorides: Synthetic Development and Opportunities
Abstract (Hetero) arylsulfur compounds where the S atom is in the oxidation state VI
represent a large percentage of the molecular functionalities present in organic chemistry …
represent a large percentage of the molecular functionalities present in organic chemistry …
Chemistry of pentafluorosulfanyl derivatives and related analogs: from synthesis to applications
Abstract Pentafluorosulfanyl (SF5)‐containing compounds and corresponding analogs are a
highly valuable class of fluorine‐containing building blocks owing to their unique properties …
highly valuable class of fluorine‐containing building blocks owing to their unique properties …
Application of the pentafluorosulfanyl group as a bioisosteric replacement
MF Sowaileh, RA Hazlitt, DA Colby - ChemMedChem, 2017 - Wiley Online Library
The success of fluorinated molecules in drug design has led medicinal chemists to search
for new fluorine‐containing substituents. A major recently developed group is the …
for new fluorine‐containing substituents. A major recently developed group is the …
Synthesis and application of pentafluorosulfanylation reagents and derived aliphatic SF5-containing building blocks
G Haufe - Tetrahedron, 2022 - Elsevier
Among the perfluorinated substituents of organic compounds, the pentafluorosulfanyl (SF 5)
group received remarkable attention in the past few decades due to its particular properties …
group received remarkable attention in the past few decades due to its particular properties …
Polyfluorinated groups in medicinal chemistry
Introduction of novel and diverse functional groups in drug discovery is always seen with
hesitancy until good activity and low toxicity characteristics are proven. The introduction of …
hesitancy until good activity and low toxicity characteristics are proven. The introduction of …
The synthesis and biological activity of pentafluorosulfanyl analogs of fluoxetine, fenfluramine, and norfenfluramine
JT Welch, DS Lim - Bioorganic & medicinal chemistry, 2007 - Elsevier
The trifluoromethyl group of fluoxetine 1 and fenfluramine and norfenfluramine, 2 and 3, was
substituted by the pentafluorosulfanyl group. On examination of the efficacy of the …
substituted by the pentafluorosulfanyl group. On examination of the efficacy of the …
Violation of the Franck-Condon Principle due to Recoil Effects<? format?> in High Energy Molecular Core-Level Photoionization
Carbon 1 s photoelectron spectra of methane are measured over a photon energy range
between 480 eV and 1200 eV. Additional components appear between the individual …
between 480 eV and 1200 eV. Additional components appear between the individual …
Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine
P Wipf, T Mo, SJ Geib, D Caridha, GS Dow… - Organic & …, 2009 - pubs.rsc.org
Synthesis and biological evaluation of the first pentafluorosulfanyl analogs of mefloquine -
Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/B911483A Royal Society …
Organic & Biomolecular Chemistry (RSC Publishing) DOI:10.1039/B911483A Royal Society …
Pentafluorosulfanyl group: an emerging tool in optoelectronic materials
JMW Chan - Journal of Materials Chemistry C, 2019 - pubs.rsc.org
The pentafluorosulfanyl (SF5) moiety is a lesser known and underutilized functional group
that displays high electronegativity, chemical and thermal stability, and low surface energy …
that displays high electronegativity, chemical and thermal stability, and low surface energy …