Picrotoxane sesquiterpenoids: chemistry, chemo-and bio-syntheses and biological activities

QQ Shi, JJ Tang, JM Gao - Natural Product Reports, 2022 - pubs.rsc.org
Covering: up to December 2021 Picrotoxane sesquiterpenoids are a special category of
natural products known to have a picrotoxane skeleton and are characterised by a highly …

Recent advances and new insights in biosynthesis of dendrobine and sesquiterpenes

DY Gong, XY Chen, SX Guo, BC Wang, B Li - Applied Microbiology and …, 2021 - Springer
Sesquiterpenes are one of the most diverse groups of secondary metabolites that have
mainly been observed in terpenoids. It is a natural terpene containing 15 carbon atoms in …

Chiral oxalamide phosphine (COAP)-Pd-catalyzed enantioselective cascade formal [4+ 1] annulation for enantioenriched 2, 3-disubstituted indolines and further DFT …

SS Zhou, JH Shen, WK Liu, XY Sun, JY Song… - Organic Chemistry …, 2023 - pubs.rsc.org
A chiral oxalamide phosphine (COAP)-Pd-catalyzed asymmetric cascade formal [4+ 1]
annulation was developed between racemic vinyl benzoxazinones and N-tosylhydrazone …

Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl

D Gong, B Wu, H Qin, D Fu, S Guo, B Wang, B Li - Amb Express, 2022 - Springer
Dendrobium nobile Lindl. has been used as a traditional Chinese medicine for a long time,
in which the most important compound is dendrobine functioning in a variety of …

Sequencing palladium-catalyzed cycloisomerization cascades in a synthesis of the gelsemine core

G Liang, EA Anderson - Chemical Science, 2023 - pubs.rsc.org
Transition metal-catalyzed cycloisomerization is a powerful strategy for the construction of
cyclic organic molecules, and the use of palladium catalysts can deliver a wide range of …

Total synthesis of terpenes via palladium-catalysed cyclization strategy

BM Trost, C Min - Nature Chemistry, 2020 - nature.com
Nature's synthetic plans to construct molecules have been developed over millions of years
of evolution and frequently prove to be among the most sophisticated. Mimicking nature's …

Catalytic enantioselective total synthesis of the picrotoxane alkaloids (−)-dendrobine,(−)-mubironine B, and (−)-dendroxine

L Guo, W Frey, B Plietker - Organic letters, 2018 - ACS Publications
A concise enantioselective total synthesis of three sesquiterpenoid alkaloids—(−)-
dendrobine,(−)-mubironine B, and (−)-dendroxine—is presented, which highlights the state …

Two unusual dendrobine-type alkaloids from Dendrobium findlayanum

D Yang, ZQ Cheng, B Hou, L Yang, CT Zi, FW Dong… - Fitoterapia, 2020 - Elsevier
Two unusual dendrobine-type alkaloids, findlayines E and F (1, 2), along with five known
dendrobine-type alkaloids (3–7), were isolated from the stems of Dendrobium findlayanum …

Synthesis of the tricyclic picrotoxane motif by an oxidative cascade cyclization

J Cao, W Thor, S Yang, M Zhang, W Bao, L Zhu… - Organic …, 2019 - ACS Publications
An oxidative cascade cyclization of β-keto esters has been developed for the construction of
the tricyclic picrotoxane motif in a single step, and DFT calculations suggested a possible …

Characterization of main degradation products from dendrobine under stress conditions by multistage cleavage of UPLC-ESI-IT-TOF

H Zhou, M Zeng, K Geng, Z Chen, Z Tang, J Xu… - … of Pharmaceutical and …, 2025 - Elsevier
Dendrobine is a sesquiterpene alkaloid primarily used in the treatment of inflammatory
diseases, immune system disorders, and conditions related to oxidative stress. To …