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Trials and tribulations of MicroRNA therapeutics
AA Seyhan - International journal of molecular sciences, 2024 - mdpi.com
The discovery of the link between microRNAs (miRNAs) and a myriad of human diseases,
particularly various cancer types, has generated significant interest in exploring their …
particularly various cancer types, has generated significant interest in exploring their …
[HTML][HTML] MicroRNA: A signature for cancer progression
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …
control expression of genes by targeting mRNAs. miRNA alterations partake in the …
[HTML][HTML] Histone modifications and non-coding RNAs: mutual epigenetic regulation and role in pathogenesis
IV Bure, MV Nemtsova, EB Kuznetsova - International Journal of …, 2022 - mdpi.com
In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …
Cross talks between oxidative stress, inflammation and epigenetics in diabetic retinopathy
RA Kowluru - Cells, 2023 - mdpi.com
Diabetic retinopathy, one of the most devastating complications of diabetes, is a
multifactorial progressing disease with a very complex etiology. Although many metabolic …
multifactorial progressing disease with a very complex etiology. Although many metabolic …
[HTML][HTML] Cisplatin resistance: genetic and epigenetic factors involved
Cisplatin (CDDP) is the drug of choice against different types of cancer. However, tumor
cells can acquire resistance to the damage caused by cisplatin, generating genetic and …
cells can acquire resistance to the damage caused by cisplatin, generating genetic and …
Emerging delivery approaches for targeted pulmonary fibrosis treatment
Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …
The mechanism of DNA methylation and miRNA in breast cancer
L Ma, C Li, H Yin, J Huang, S Yu, J Zhao… - International Journal of …, 2023 - mdpi.com
Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …
The Role of non-coding RNAs in colorectal cancer, with a focus on its autophagy
L Chen, M He, M Zhang, Q Sun, S Zeng, H Zhao… - Pharmacology & …, 2021 - Elsevier
Colorectal cancer (CRC) is one of malignant afflictions burdening people worldwide, mainly
caused by shortages of effective medical intervention and poorly mechanistic understanding …
caused by shortages of effective medical intervention and poorly mechanistic understanding …
Decoding the role of miRNAs in multiple myeloma pathogenesis: a focus on signaling pathways
Multiple myeloma (MM) is a cancer of plasma cells that has been extensively studied in
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …
RNA-based therapies: A cog in the wheel of lung cancer defense
Lung cancer (LC) is a heterogeneous disease consisting mainly of two subtypes, non-small
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …
cell lung cancer (NSCLC) and small cell lung cancer (SCLC), and remains the leading …