Cancers represent complex ecosystems comprising tumor cells and a multitude of non-
cancerous cells, embedded in an altered extracellular matrix. The tumor microenvironment …

Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Artificial intelligence (AI) has emerged as a crucial tool in healthcare with the primary aim of
improving patient outcomes and optimizing healthcare delivery. By harnessing machine …

Summary p53 was discovered 45 years ago as an SV40 large T antigen binding protein,
coded by the most frequently mutated TP53 gene in human cancers. As a transcription …

With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Advances in quantitative biomarker development have accelerated new forms of data-driven
insights for patients with cancer. However, most approaches are limited to a single mode of …

Epigenetic dysregulation is a common feature of a myriad of human diseases, particularly
cancer. Defining the epigenetic defects associated with malignant tumors has become a …

Cancer is a leading cause of morbidity and mortality worldwide. While progress has been
made in the diagnosis, prognosis, and treatment of cancer patients, individualized and data …

Artificial intelligence (AI) in healthcare plays a pivotal role in combating many fatal diseases,
such as skin, breast, and lung cancer. AI is an advanced form of technology that uses …

Tailoring optimal treatment for individual cancer patients remains a significant challenge. To
address this issue, we developed PERCEPTION (PERsonalized Single-Cell Expression …