Type 2 diabetes mellitus (T2DM) is characterized by tissue-specific insulin resistance and
pancreatic β-cell dysfunction, which result from the interplay of local abnormalities within …

Adipokines play a significant role in cardiometabolic diseases. Asprosin, a newly discovered
adipokine, was first identified as a glucose-raising protein hormone. Asprosin also …

Adipose tissue is a dynamic endocrine organ, secreting a plethora of adipokines which play
a key role in regulating metabolic homeostasis and other physiological processes. An …

Background Altered adipokine secretion in dysfunctional adipose tissue facilitates the
development of atherosclerotic diseases including lower extremity peripheral artery disease …

Fibrillin-1 is a major component of the extracellular microfibrils, where it interacts with other
extracellular matrix proteins to provide elasticity to connective tissues, and regulates the …

Vascular endothelium dysfunction caused by endothelium inflammation is a trigger of
numerous cardiovascular diseases. Vascular endothelium inflammation often occurs in …

Asprosin, a fasting-induced, glucogenic, and orexigenic adipokine, has gained popularity in
recent years as a potential target in the fight against obesity and its complications. However …

Asprosin (ASP) is a recently identified adipokine secreted by white adipose tissue (WAT). It
plays important roles in the maintenance of glucose homeostasis in the fasting state and in …

Background Nonalcoholic fatty liver disease (NAFLD) is a primary contributor to liver‐related
morbidity and mortality. Asprosin has been reported to be implicated in NAFLD. Aims This …

Asprosin, encoded by penultimate two exons (exon 65 and exon 66) of the gene Fibrillin 1
(FBN1), has been recently discovered to be a novel hormone secreted by white adipose …