[HTML][HTML] State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018
E Mahanna-Gabrielli, KJ Schenning, LI Eriksson… - British journal of …, 2019 - Elsevier
Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families,
and caregivers. Reports of patients who were 'never the same'prompted a scientific inquiry …
and caregivers. Reports of patients who were 'never the same'prompted a scientific inquiry …
Association of postoperative delirium with cognitive outcomes: a meta-analysis
H Huang, H Li, X Zhang, G Shi, M Xu, X Ru… - Journal of Clinical …, 2021 - Elsevier
Study objective To determine the association between postoperative delirium (POD) and
cognitive outcomes at least 1 month after surgery in elderly patients, and synthesize the …
cognitive outcomes at least 1 month after surgery in elderly patients, and synthesize the …
[HTML][HTML] Anaesthetic depth and delirium after major surgery: a randomised clinical trial
Background Postoperative delirium is a serious complication of surgery associated with
prolonged hospitalisation, long-term cognitive decline, and mortality. This study aimed to …
prolonged hospitalisation, long-term cognitive decline, and mortality. This study aimed to …
Association of delirium with long-term cognitive decline: a meta-analysis
Importance Delirium is associated with increased hospital costs, health care complications,
and increased mortality. Long-term consequences of delirium on cognition have not been …
and increased mortality. Long-term consequences of delirium on cognition have not been …
One-year medicare costs associated with delirium in older patients undergoing major elective surgery
Importance Delirium is a common, serious, and potentially preventable problem for older
adults, associated with adverse outcomes. Coupled with its preventable nature, these …
adults, associated with adverse outcomes. Coupled with its preventable nature, these …
Effect of intravenous acetaminophen vs placebo combined with propofol or dexmedetomidine on postoperative delirium among older patients following cardiac …
Importance Postoperative delirium is common following cardiac surgery and may be affected
by choice of analgesic and sedative. Objective To evaluate the effect of postoperative …
by choice of analgesic and sedative. Objective To evaluate the effect of postoperative …
[HTML][HTML] Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study
T Ballweg, M White, M Parker, C Casey, A Bo… - British journal of …, 2021 - Elsevier
Background Postoperative delirium is associated with increases in the neuronal injury
biomarker, neurofilament light (NfL). Here we tested whether two other biomarkers, glial …
biomarker, neurofilament light (NfL). Here we tested whether two other biomarkers, glial …
Association between perioperative medication use and postoperative delirium and cognition in older adults undergoing elective noncardiac surgery
BACKGROUND: Postoperative delirium is frequent in older adults and is associated with
postoperative neurocognitive disorder (PND). Studies evaluating perioperative medication …
postoperative neurocognitive disorder (PND). Studies evaluating perioperative medication …
Intraoperative oxygen concentration and neurocognition after cardiac surgery: a randomized clinical trial
BACKGROUND: Despite evidence suggesting detrimental effects of perioperative
hyperoxia, hyperoxygenation remains commonplace in cardiac surgery. Hyperoxygenation …
hyperoxia, hyperoxygenation remains commonplace in cardiac surgery. Hyperoxygenation …
Clinical EEG slowing correlates with delirium severity and predicts poor clinical outcomes
EY Kimchi, A Neelagiri, W Whitt, AR Sagi, SL Ryan… - Neurology, 2019 - AAN Enterprises
Objective To determine which findings on routine clinical EEGs correlate with delirium
severity across various presentations and to determine whether EEG findings independently …
severity across various presentations and to determine whether EEG findings independently …