[HTML][HTML] State of the clinical science of perioperative brain health: report from the American Society of Anesthesiologists Brain Health Initiative Summit 2018

E Mahanna-Gabrielli, KJ Schenning, LI Eriksson… - British journal of …, 2019 - Elsevier
Cognitive recovery after anaesthesia and surgery is a concern for older adults, their families,
and caregivers. Reports of patients who were 'never the same'prompted a scientific inquiry …

Association of postoperative delirium with cognitive outcomes: a meta-analysis

H Huang, H Li, X Zhang, G Shi, M Xu, X Ru… - Journal of Clinical …, 2021 - Elsevier
Study objective To determine the association between postoperative delirium (POD) and
cognitive outcomes at least 1 month after surgery in elderly patients, and synthesize the …

[HTML][HTML] Anaesthetic depth and delirium after major surgery: a randomised clinical trial

LA Evered, MTV Chan, R Han, MHM Chu… - British journal of …, 2021 - Elsevier
Background Postoperative delirium is a serious complication of surgery associated with
prolonged hospitalisation, long-term cognitive decline, and mortality. This study aimed to …

Association of delirium with long-term cognitive decline: a meta-analysis

TE Goldberg, C Chen, Y Wang, E Jung… - JAMA …, 2020 - jamanetwork.com
Importance Delirium is associated with increased hospital costs, health care complications,
and increased mortality. Long-term consequences of delirium on cognition have not been …

One-year medicare costs associated with delirium in older patients undergoing major elective surgery

RY Gou, TT Hshieh, ER Marcantonio, Z Cooper… - JAMA …, 2021 - jamanetwork.com
Importance Delirium is a common, serious, and potentially preventable problem for older
adults, associated with adverse outcomes. Coupled with its preventable nature, these …

Effect of intravenous acetaminophen vs placebo combined with propofol or dexmedetomidine on postoperative delirium among older patients following cardiac …

B Subramaniam, P Shankar, S Shaefi, A Mueller… - Jama, 2019 - jamanetwork.com
Importance Postoperative delirium is common following cardiac surgery and may be affected
by choice of analgesic and sedative. Objective To evaluate the effect of postoperative …

[HTML][HTML] Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study

T Ballweg, M White, M Parker, C Casey, A Bo… - British journal of …, 2021 - Elsevier
Background Postoperative delirium is associated with increases in the neuronal injury
biomarker, neurofilament light (NfL). Here we tested whether two other biomarkers, glial …

Association between perioperative medication use and postoperative delirium and cognition in older adults undergoing elective noncardiac surgery

MS Duprey, JW Devlin, JL Griffith… - Anesthesia & …, 2022 - journals.lww.com
BACKGROUND: Postoperative delirium is frequent in older adults and is associated with
postoperative neurocognitive disorder (PND). Studies evaluating perioperative medication …

Intraoperative oxygen concentration and neurocognition after cardiac surgery: a randomized clinical trial

S Shaefi, P Shankar, AL Mueller, BP O'Gara… - …, 2021 - pmc.ncbi.nlm.nih.gov
BACKGROUND: Despite evidence suggesting detrimental effects of perioperative
hyperoxia, hyperoxygenation remains commonplace in cardiac surgery. Hyperoxygenation …

Clinical EEG slowing correlates with delirium severity and predicts poor clinical outcomes

EY Kimchi, A Neelagiri, W Whitt, AR Sagi, SL Ryan… - Neurology, 2019 - AAN Enterprises
Objective To determine which findings on routine clinical EEGs correlate with delirium
severity across various presentations and to determine whether EEG findings independently …