Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics
with cell-type specificity. However, current indicators enable a narrow range of applications …

Optical interrogation of voltage in deep brain locations with cellular resolution would be
immensely useful for understanding how neuronal circuits process information. Here, we …

A remaining challenge for genetically encoded voltage indicators (GEVIs) is the reliable
detection of excitatory postsynaptic potentials (EPSPs). Here, we developed ASAP5 as a …

GABAergic interneurons in the hippocampus provide for local and long-distance
coordination of neurons in functionally connected areas. Vasoactive intestinal peptide …

Optical recording of neuronal activity in three-dimensional (3D) brain circuits at cellular and
millisecond resolution in vivo is essential for probing information flow in the brain. While …

Disinhibition is a widespread circuit mechanism for information selection and transfer. In the
hippocampus, disinhibition of principal cells is provided by the interneuron-specific …

Neurons in the mouse auditory cortex are strongly influenced by behavior, including both
suppression and enhancement of sound-evoked responses during movement. The mouse …

The CA1 region of the hippocampus contains both glutamatergic pyramidal cells and
GABAergic interneurons. Numerous reports have characterized glutamatergic CAMK2A cell …

Distinctions between cell types underpin organizational principles for nervous system
function. Functional variation also exists between neurons of the same type. This is …

Hippocampal inhibitory interneurons exhibit a large diversity of dendritic Ca2+ mechanisms
that are involved in the induction of Hebbian and anti-Hebbian synaptic plasticity. High …