[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease
T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …
also increasing. According to current estimates, approximately 11% of people over 65 suffer …
Heterogeneity of mesenchymal stem cell-derived extracellular vesicles is highly impacted by the tissue/cell source and culture conditions
C Almeria, S Kreß, V Weber, D Egger, C Kasper - Cell & Bioscience, 2022 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures exerting major effects in
physiological as well as pathological processes by functioning as vehicles for the delivery of …
physiological as well as pathological processes by functioning as vehicles for the delivery of …
Cell culture‐derived extracellular vesicles: Considerations for reporting cell culturing parameters
Cell culture‐conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs)
for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect …
for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect …
Comparative analysis of magnetically activated cell sorting and ultracentrifugation methods for exosome isolation
Mesenchymal stem cell-derived exosomes regulate cell migration, proliferation,
differentiation, and synthesis of the extracellular matrix, giving great potential for the …
differentiation, and synthesis of the extracellular matrix, giving great potential for the …
Regenerative potential of different extracellular vesicle subpopulations derived from clonal mesenchymal stem cells in a mouse model of chemotherapy-induced …
N Eslami, K Bahrehbar, F Esfandiari, F Shekari… - Life Sciences, 2023 - Elsevier
Aims Some studies have shown that mesenchymal stem cells (MSCs) and their derived
extracellular vesicles (MSC-EVs) can restore ovarian function in premature ovarian failure …
extracellular vesicles (MSC-EVs) can restore ovarian function in premature ovarian failure …
Homogenous subpopulation of human mesenchymal stem cells and their extracellular vesicles restore function of endometrium in an experimental rat model of …
N Mansouri-Kivaj, A Nazari, F Esfandiari… - Stem Cell Research & …, 2023 - Springer
Background Asherman syndrome (AS), or intrauterine adhesions, is a main cause of
infertility in reproductive age women after endometrial injury. Mesenchymal stem cells …
infertility in reproductive age women after endometrial injury. Mesenchymal stem cells …
Extracellular vesicles and their cells of origin: Open issues in autoimmune diseases
The conventional therapeutic approaches to treat autoimmune diseases through
suppressing the immune system, such as steroidal and non-steroidal anti-inflammatory …
suppressing the immune system, such as steroidal and non-steroidal anti-inflammatory …
Extracellular vesicles from mesenchymal stromal cells: Therapeutic perspectives for targeting senescence in osteoarthritis
Osteoarthritis (OA) is a common age-related disease that correlates with a high number of
senescent cells in joint tissues. Senescence has been reported to be one of the main drivers …
senescent cells in joint tissues. Senescence has been reported to be one of the main drivers …
Mesenchymal stem cell-derived extracellular vesicles in therapy against fibrotic diseases
Y Huang, L Yang - Stem Cell Research & Therapy, 2021 - Springer
Fibrosis is likely to occur in many tissues and organs to induce cicatrisation and dysfunction.
The therapeutic regimens for delaying and even reversing fibrosis are quite limited at …
The therapeutic regimens for delaying and even reversing fibrosis are quite limited at …
Extracellular vesicles as reconfigurable therapeutics for eye diseases: Promises and hurdles
A large number of people worldwide suffer from visual impairment. However, most available
therapies rely on impeding the development of a particular eye disorder. Therefore, there is …
therapies rely on impeding the development of a particular eye disorder. Therefore, there is …