Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Candida albicans and Candida glabrata: global priority pathogens

M Katsipoulaki, MHT Stappers… - Microbiology and …, 2024 - journals.asm.org
SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

Vulvovaginal candidiasis: a current understanding and burning questions

HME Willems, SS Ahmed, J Liu, Z Xu, BM Peters - Journal of Fungi, 2020 - mdpi.com
Candida albicans, along with other closely related Candida species, are the primary
causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of …

Fungal microbiota dysbiosis in IBD

H Sokol, V Leducq, H Aschard, HP Pham, S Jegou… - Gut, 2017 - gut.bmj.com
Objective The bacterial intestinal microbiota plays major roles in human physiology and
IBDs. Although some data suggest a role of the fungal microbiota in IBD pathogenesis, the …

Vulvovaginal candidiasis: Epidemiology, microbiology and risk factors

B Gonçalves, C Ferreira, CT Alves… - Critical reviews in …, 2016 - Taylor & Francis
Vulvovaginal candidiasis (VVC) is an infection caused by Candida species that affects
millions of women every year. Although Candida albicans is the main cause of VVC, the …

Innate immune pattern recognition: a cell biological perspective

SW Brubaker, KS Bonham, I Zanoni… - Annual review of …, 2015 - annualreviews.org
Receptors of the innate immune system detect conserved determinants of microbial and viral
origin. Activation of these receptors initiates signaling events that culminate in an effective …

Immune defence against Candida fungal infections

MG Netea, LAB Joosten, JWM Van Der Meer… - Nature Reviews …, 2015 - nature.com
The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance

D Daley, VR Mani, N Mohan, N Akkad, A Ochi… - Nature medicine, 2017 - nature.com
The progression of pancreatic oncogenesis requires immune-suppressive inflammation in
cooperation with oncogenic mutations. However, the drivers of intratumoral immune …