Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs
W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …
Recent developments in the medicinal applications of silver-NHC complexes and imidazolium salts
NA Johnson, MR Southerland, WJ Youngs - Molecules, 2017 - mdpi.com
Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …
Recent developments of metal N-heterocyclic carbenes as anticancer agents
Metal based anticancer drugs have demonstrated their crucial role in preventing all types of
cancers whereas their effectiveness is selective with respect to the cancer cells rather than …
cancers whereas their effectiveness is selective with respect to the cancer cells rather than …
Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications
New weapons are constantly needed in the fight against cancer. The discovery of cisplatin
as an anticancer drug prompted the search for new metal complexes. The successful history …
as an anticancer drug prompted the search for new metal complexes. The successful history …
Novel 2-methylimidazolium salts: Synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties
In this work, structures of different imidazolium compounds were designed and synthesized.
These compounds were synthesized from 2-methylimidazole and alkyl/aryl halides. Their …
These compounds were synthesized from 2-methylimidazole and alkyl/aryl halides. Their …
Biologically Relevant Silver (I)–N‐Heterocyclic Carbene Complexes: Synthesis, Structure, Intramolecular Interactions, and Applications
N‐Heterocyclic carbenes (NHCs) complexed with silver represent new, broad‐spectrum
antimicrobial and anticancer agents, normally with low toxicity profiles, and they provide a …
antimicrobial and anticancer agents, normally with low toxicity profiles, and they provide a …
Group XII metal–N-heterocyclic carbene complexes: synthesis, structural diversity, intramolecular interactions, and applications
This review covers the different methods for the synthesis of group XII metal–NHC
complexes with five-and six-membered NHC systems that have different N-heterocyclic …
complexes with five-and six-membered NHC systems that have different N-heterocyclic …
New compounds based on a benzimidazole nucleus: synthesis, characterization and cytotoxic activity against breast and colon cancer cell lines
Benzimidazolium salts and their Pyridine Enhanced Precatalyst Preparation Stabilization
and I nitiation (PEPPSI) palladium N-heterocyclic carbene (Pd-NHC) based complexes have …
and I nitiation (PEPPSI) palladium N-heterocyclic carbene (Pd-NHC) based complexes have …
Potential of silver against human colon cancer: (synthesis, characterization and crystal structures of xylyl (Ortho, meta, & Para) linked bis-benzimidazolium salts and Ag(I)-NHC …
Background Since the first successful synthesis of Ag (I)-N-heterocyclic carbene complex in
1993, this class of compounds has been extensively used for transmetallation reactions …
1993, this class of compounds has been extensively used for transmetallation reactions …
Novel N-heterocyclic carbene silver (I) complexes: Synthesis, structural characterization, and anticancer activity
In this study, we synthesized four novel unsymmetrically substituted NHC ligands (1a-d) and
their Ag (I) complexes (2a-d). All new compounds were characterized using elemental …
their Ag (I) complexes (2a-d). All new compounds were characterized using elemental …