It has long been recognized that certain sites within a protein, such as sites in the protein
core or catalytic residues in enzymes, are evolutionarily more conserved than other sites …

The zoonotic origin of the COVID-19 pandemic virus highlights the need to fill the vast gaps
in our knowledge of SARS-CoV-2 ecology and evolution in non-human hosts. Here, we …

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection
in young children and the second leading cause of infant death worldwide. While global …

Swine influenza presents a substantial disease burden for pig populations worldwide and
poses a potential pandemic threat to humans. There is considerable diversity in both H1 and …

ABSTRACT H5N1 high pathogenicity avian influenza (HPAI) viruses of the clade 2.3. 4.4 b
have killed thousands of marine mammals in South America since 2022. In October 2023 …

Lassa virus is an Old World arenavirus endemic to West Africa that causes severe
hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein …

Efficient algorithms and programs for the analysis of the ever-growing amount of biological
sequence data are strongly needed in the genomics era. The pace at which new data and …

The global-scale epidemiology and genome-wide evolutionary dynamics of influenza B
remain poorly understood compared with influenza A viruses. We compiled a spatio …

The process of speciation, by definition, involves evolution of one or more reproductive
isolating mechanisms that split a single species into two that can no longer interbreed …

Genomic variation and related evolutionary dynamics of human respiratory syncytial virus
(RSV), a common causative agent of severe lower respiratory tract infections, may affect its …