[HTML][HTML] Effects of endocrine disrupting chemicals on gonad development: Mechanistic insights from fish and mammals

G Delbes, M Blázquez, JI Fernandino, P Grigorova… - Environmental …, 2022 - Elsevier
Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs)
have an impact on reproductive health. An increased frequency of reproductive disorders …

Comparing postnatal development of gonadal hormones and associated social behaviors in rats, mice, and humans

MR Bell - Endocrinology, 2018 - academic.oup.com
Postnatal development includes dramatic changes in gonadal hormones and the many
social behaviors they help regulate, both in rodents and humans. Parental care-seeking is …

Dissecting cell lineage specification and sex fate determination in gonadal somatic cells using single-cell transcriptomics

I Stévant, F Kühne, A Greenfield, MC Chaboissier… - Cell reports, 2019 - cell.com
Sex determination is a unique process that allows the study of multipotent progenitors and
their acquisition of sex-specific fates during differentiation of the gonad into a testis or an …

Complete in vitro generation of fertile oocytes from mouse primordial germ cells

K Morohaku, R Tanimoto, K Sasaki… - Proceedings of the …, 2016 - National Acad Sciences
Reconstituting gametogenesis in vitro is a key goal for reproductive biology and
regenerative medicine. Successful in vitro reconstitution of primordial germ cells and …

How is the number of primordial follicles in the ovarian reserve established?

JK Findlay, KJ Hutt, M Hickey… - Biology of …, 2015 - academic.oup.com
The number of primordial follicles in the ovarian reserve is an important determinant of the
length of the ovarian lifespan, and therefore the fertility of an individual. This reserve …

The developmental origins of the mammalian ovarian reserve

KJ Grive, RN Freiman - Development, 2015 - journals.biologists.com
The adult mammalian ovary is devoid of definitive germline stem cells. As such, female
reproductive senescence largely results from the depletion of a finite ovarian follicle pool …

At the crossroads of fate—somatic cell lineage specification in the fetal gonad

E Rotgers, A Jørgensen, HHC Yao - Endocrine reviews, 2018 - academic.oup.com
The reproductive endocrine systems are vastly different between males and females. This
sexual dimorphism of the endocrine milieu originates from sex-specific differentiation of the …

The effect of garlic on lipid profile and glucose parameters in diabetic patients: A systematic review and meta-analysis

E Shabani, K Sayemiri, M Mohammadpour - Primary care diabetes, 2019 - Elsevier
Purpose Several studies have been published about the effect of garlic on lipid profile and
blood glucose in diabetic patients. Which, the results mostly contradict with each other. This …

Mechanisms controlling germline cyst breakdown and primordial follicle formation

C Wang, B Zhou, G **a - Cellular and Molecular Life Sciences, 2017 - Springer
In fetal females, oogonia proliferate immediately after sex determination. The progress of
mitosis in oogonia proceeds so rapidly that the incompletely divided cytoplasm of the sister …

Dysfunctional ovarian stem cells due to neonatal endocrine disruption result in PCOS and ovarian insufficiency in adult mice

D Sharma, D Bhartiya - Stem Cell Reviews and Reports, 2022 - Springer
Polycystic ovarian syndrome (PCOS) is a common global cause of anovulatory infertility but
underlying etiology leading to PCOS still remains elusive. Fetal and perinatal endocrine …