Metal–organic frameworks encapsulated with an anticancer compound as drug delivery system: Synthesis, characterization, antioxidant, anticancer, antibacterial, and …

MA El‐Bindary, MG El‐Desouky… - Applied …, 2022 - Wiley Online Library
Metal organic framework (MOF) hybrid materials could be one of the answers in this
investigation. We describe a simple and effective encapsulation of doxorubicin (DOX), an …

A comprehensive survey upon diverse and prolific applications of chitosan-based catalytic systems in one-pot multi-component synthesis of heterocyclic rings

H Mousavi - International Journal of Biological Macromolecules, 2021 - Elsevier
Heterocyclic compounds are among the most prestigious and valuable chemical molecules
with diverse and magnificent applications in various sciences. Due to the remarkable and …

A review on biological and medicinal significance of thiazoles

PM Jadhav, S Kantevari, AB Tekale… - … , Sulfur, and Silicon …, 2021 - Taylor & Francis
Thiazole, a five-membered heterocyclic compound constitutes the skeleton of various
commercially marketed drug candidates and the heart-core in a diverse range of entities of …

Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

TA Farghaly, GS Masaret, ZA Muhammad… - Bioorganic chemistry, 2020 - Elsevier
The crucial need for novel antitumor agents with high selectivity toward cancer cells has
promoted us to synthesize new series of thiazole-based chalcones and 4-hetarylthiazoles …

One-pot synthesis of novel thiazoles as potential anti-cancer agents

AR Sayed, SM Gomha, EA Taher… - Drug design …, 2020 - Taylor & Francis
Background Thiazole and thiosemicarbazone derivatives are known to have potential
anticancer activity with a mechanism of action related to inhibition of matrix metallo …

Mechanochemical synthesis and molecular docking studies of new azines bearing indole as anticancer agents

MS Ibrahim, B Farag, J Y. Al-Humaidi, MEA Zaki… - Molecules, 2023 - mdpi.com
The development of new approaches for the synthesis of new bioactive heterocyclic
derivatives is of the utmost importance for pharmaceutical industry. In this regard, the …

Clean grinding technique: A facile synthesis and in silico antiviral activity of hydrazones, pyrazoles, and pyrazines bearing thiazole moiety against SARS-CoV-2 main …

S Abu-Melha, MM Edrees, SM Riyadh, MR Abdelaziz… - Molecules, 2020 - mdpi.com
A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop
grinding of thiazole carbohydrazide 2 with various carbonyl compounds. Also, dehydrative …

[HTML][HTML] Green synthesis and molecular docking study of some new thiazoles using terephthalohydrazide chitosan hydrogel as ecofriendly biopolymeric catalyst

JY Al-Humaidi, SM Gomha, NAA El-Ghany, B Farag… - Catalysts, 2023 - mdpi.com
Terephthalohydrazide chitosan hydrogel (TCs) was prepared and investigated as an
ecofriendly biopolymeric catalyst for synthesis of some novel thiazole and thiadiazole …

Nano-synthesis approach, elaborated spectral, biological activity and in silico assessment of novel nano-metal complexes based on sulfamerazine azo dye

AM Khedr, AA Gouda, HA El‑Ghamry - Journal of Molecular Liquids, 2022 - Elsevier
Novel mono-and homo bi-nuclear chelates of sulfamerazine-resorcinol azo-dye ligand (H 3
L) for pharmaceutical applications were acquired by coupling of sulfamerazine diazonium …

Three-component synthesis of some new coumarin derivatives as anticancer agents

LA Alshabanah, LA Al-Mutabagani, SM Gomha… - Frontiers in …, 2022 - frontiersin.org
A three-component reaction for the synthesis of novel 3-heteroaryl-coumarin utilizing
acetylcoumarin synthon under ultrasonic irradiation was developed using chitosan-grafted …