The treat-to-target (T2T) concept has improved outcomes for patients with diabetes,
hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well …

In the past decade, the emergence of machine learning (ML) applications has led to
significant advances towards implementation of personalised medicine approaches for …

Objective To evaluate disease activity statuses'(DAS') impact on systemic lupus
erythematosus (SLE) outcomes. Materials and methods Four DAS were defined: remission …

Objective. To determine nephritis outcomes in a prospective multi-ethnic/racial SLE
inception cohort. Methods. Patients in the Systemic Lupus International Collaborating Clinics …

Abstract Objective The Systemic Lupus International Collaborating Clinics (SLICC) group
revised and validated the American College of Rheumatology (ACR) systemic lupus …

Objectives Treat-to-target recommendations have identified 'remission'as a target in
systemic lupus erythematosus (SLE), but recognise that there is no universally accepted …

Caroline Gordon1, 2, 3, Maame-Boatemaa Amissah-Arthur1, Mary Gayed1, 3, Sue Brown4,
Ian N. Bruce5, 6, David D'Cruz7, Benjamin Empson8, Bridget Griffiths9, David Jayne10, 11 …

The principle of treating-to-target has been successfully applied to many diseases outside
rheumatology and more recently to rheumatoid arthritis. Identifying appropriate therapeutic …

Background and aims We studied damage accrual and factors determining development
and progression of damage in an international cohort of systemic lupus erythematosus …

Background Systemic lupus erythematosus (SLE) is an autoimmune disease with a
prevalence of 36.7/100 000 in Germany and a female/male ratio of 4: 1. The clinical course …