Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications

R Nasiri, A Shamloo, S Ahadian, L Amirifar, J Akbari… - Small, 2020 - Wiley Online Library
Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

A review of secondary flow in inertial microfluidics

Q Zhao, D Yuan, J Zhang, W Li - Micromachines, 2020 - mdpi.com
Inertial microfluidic technology, which can manipulate the target particle entirely relying on
the microchannel characteristic geometry and intrinsic hydrodynamic effect, has attracted …

Recent advances in multimode microfluidic separation of particles and cells

Y Song, D Li, X Xuan - Electrophoresis, 2023 - Wiley Online Library
Microfluidic separation of particles and cells is crucial to lab‐on‐a‐chip applications in the
fields of science, engineering, and industry. The continuous‐flow separation methods can …

Hybrid microfluidics combined with active and passive approaches for continuous cell separation

S Yan, J Zhang, D Yuan, W Li - Electrophoresis, 2017 - Wiley Online Library
Microfluidics, which is classified as either active or passive, is capable of separating cells of
interest from a complex and heterogeneous sample. Active methods utilise external fields …

Continuous separation of particles in a PDMS microfluidic channel via travelling surface acoustic waves (TSAW)

G Destgeer, KH Lee, JH Jung, A Alazzam, HJ Sung - Lab on a Chip, 2013 - pubs.rsc.org
We demonstrate a simple and efficient device for the continuous label-free separation of
microparticles using travelling surface acoustic waves (TSAW). A focusing interdigitated …

Microchannel anechoic corner for size-selective separation and medium exchange via traveling surface acoustic waves

G Destgeer, BH Ha, J Park, JH Jung… - Analytical …, 2015 - ACS Publications
We demonstrate a miniaturized acoustofluidic device composed of a pair of slanted
interdigitated transducers (SIDTs) and a polydimethylsiloxane microchannel for achieving …

A comprehensive review of pinch flow fractionation in microfluidics: From principles to practical applications

SN Ashrafizadeh, M Zare, M Khatibi - Chemical Engineering and …, 2024 - Elsevier
Pinch flow fractionation (PFF) is a microfluidic-based passive technique for particle
separation that has numerous scientific applications. The efficiency of this technique is …

Selective particle and cell capture in a continuous flow using micro-vortex acoustic streaming

DJ Collins, BL Khoo, Z Ma, A Winkler, R Weser… - Lab on a Chip, 2017 - pubs.rsc.org
Acoustic streaming has emerged as a promising technique for refined microscale
manipulation, where strong rotational flow can give rise to particle and cell capture. In …

Continuous microfluidic particle separation via elasto-inertial pinched flow fractionation

X Lu, X Xuan - Analytical chemistry, 2015 - ACS Publications
Many of the fluids encountered in chemical and biomedical applications exhibit non-
Newtonian behavior. However, the majority of current particle separation methods have …