Ultra-high field MRI: Advancing systems neuroscience towards mesoscopic human brain function

SO Dumoulin, A Fracasso, W van der Zwaag… - Neuroimage, 2018 - Elsevier
Human MRI scanners at ultra-high magnetic field strengths of 7 T and higher are
increasingly available to the neuroscience community. A key advantage brought by ultra …

[HTML][HTML] Layer-dependent functional connectivity methods

L Huber, ES Finn, Y Chai, R Goebel, R Stirnberg… - Progress in …, 2021 - Elsevier
Recent methodological advances in fMRI contrast and readout strategies have allowed
researchers to approach the mesoscopic spatial regime of cortical layers. This has …

[HTML][HTML] LayNii: A software suite for layer-fMRI

LR Huber, BA Poser, PA Bandettini, K Arora, K Wagstyl… - NeuroImage, 2021 - Elsevier
High-resolution fMRI in the sub-millimeter regime allows researchers to resolve brain activity
across cortical layers and columns non-invasively. While these high-resolution data make it …

Quantifying the microvascular origin of BOLD-fMRI from first principles with two-photon microscopy and an oxygen-sensitive nanoprobe

L Gagnon, S Sakadžić, F Lesage… - Journal of …, 2015 - jneurosci.org
The blood oxygenation level-dependent (BOLD) contrast is widely used in functional
magnetic resonance imaging (fMRI) studies aimed at investigating neuronal activity …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

[HTML][HTML] Sub-millimeter fMRI reveals multiple topographical digit representations that form action maps in human motor cortex

L Huber, ES Finn, DA Handwerker, M Bönstrup… - Neuroimage, 2020 - Elsevier
The human brain coordinates a wide variety of motor activities. On a large scale, the cortical
motor system is topographically organized such that neighboring body parts are represented …

Cortical lamina-dependent blood volume changes in human brain at 7 T

L Huber, J Goense, AJ Kennerley, R Trampel, M Guidi… - Neuroimage, 2015 - Elsevier
Cortical layer-dependent high (sub-millimeter) resolution functional magnetic resonance
imaging (fMRI) in human or animal brain can be used to address questions regarding the …

Analysis strategies for high-resolution UHF-fMRI data

JR Polimeni, V Renvall, N Zaretskaya, B Fischl - Neuroimage, 2018 - Elsevier
Functional MRI (fMRI) benefits from both increased sensitivity and specificity with increasing
magnetic field strength, making it a key application for Ultra-High Field (UHF) MRI scanners …

[HTML][HTML] Physiologically informed dynamic causal modeling of fMRI data

M Havlicek, A Roebroeck, K Friston, A Gardumi… - Neuroimage, 2015 - Elsevier
The functional MRI (fMRI) signal is an indirect measure of neuronal activity. In order to
deconvolve the neuronal activity from the experimental fMRI data, biophysical generative …

Techniques for blood volume fMRI with VASO: From low-resolution map** towards sub-millimeter layer-dependent applications

L Huber, D Ivanov, DA Handwerker, S Marrett, M Guidi… - Neuroimage, 2018 - Elsevier
Quantitative cerebral blood volume (CBV) fMRI has the potential to overcome several
specific limitations of BOLD fMRI. It provides direct physiological interpretability and …