The novel coronavirus infection (COVID-19) is caused by the new coronavirus SARS-CoV-2
and is characterized by an exaggerated inflammatory response that can lead to severe …

Sepsis remains a major cause of morbidity and mortality in both low-and high-income
countries. Antibiotic therapy and supportive care have significantly improved survival …

Background There is a need to better define the epidemiology of sepsis in intensive care
units (ICUs) around the globe. Methods The Intensive Care over Nations (ICON) audit …

Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function …

Importance Septic shock currently refers to a state of acute circulatory failure associated with
infection. Emerging biological insights and reported variation in epidemiology challenge the …

Sepsis, severe sepsis, and septic shock represent increasingly severe systemic
inflammatory responses to infection. Sepsis is common in the aging population, and it …

Epidemiology of sepsis and septic shock : Current Opinion in Anesthesiology Epidemiology of
sepsis and septic shock : Current Opinion in Anesthesiology Log in or Register Subscribe to …

Background The consensus definition of severe sepsis requires suspected or proven
infection, organ failure, and signs that meet two or more criteria for the systemic inflammatory …

Importance Severe sepsis and septic shock are major causes of mortality in intensive care
unit (ICU) patients. It is unknown whether progress has been made in decreasing their …

Sepsis is a highly complex and lethal syndrome with highly heterogeneous clinical
manifestations that makes it difficult to detect and treat. It is also one of the major and most …