Vascular inflammatory diseases and endothelial phenotypes

J Immanuel, S Yun - Cells, 2023 - mdpi.com
The physiological functions of endothelial cells control vascular tone, permeability,
inflammation, and angiogenesis, which significantly help to maintain a healthy vascular …

Intracoronary imaging of coronary atherosclerotic plaque: from assessment of pathophysiological mechanisms to therapeutic implication

FL Gurgoglione, A Denegri, M Russo… - International journal of …, 2023 - mdpi.com
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality
worldwide. Several cardiovascular risk factors are implicated in atherosclerotic plaque …

Advances in the computational assessment of disturbed coronary flow and wall shear stress: a contemporary review

AA Ekmejian, HJ Carpenter, JL Ciofani… - Journal of the …, 2024 - ahajournals.org
Coronary artery blood flow is influenced by various factors including vessel geometry,
hemodynamic conditions, timing in the cardiac cycle, and rheological conditions. Multiple …

Impact of endothelial shear stress on coronary atherosclerotic plaque progression and composition: A meta-analysis and systematic review

A Candreva, AL Buongiorno, MA Matter… - International Journal of …, 2024 - Elsevier
Background and aims Intracoronary pressure gradients and translesional flow patterns have
been correlated with coronary plaque progression and lesion destabilization. In this study …

A parametric study of the effect of 3D plaque shape on local hemodynamics and implications for plaque instability

SS Hossain, MJ Johnson, TJR Hughes - Biomechanics and Modeling in …, 2024 - Springer
The vast majority of heart attacks occur when vulnerable plaques rupture, releasing their
lipid content into the blood stream leading to thrombus formation and blockage of a coronary …

Biomechanical factors and atherosclerosis localization: insights and clinical applications

E Bacigalupi, J Pizzicannella, G Rigatelli… - Frontiers in …, 2024 - frontiersin.org
Although the entire vascular bed is constantly exposed to the same risk factors,
atherosclerosis manifests a distinct intra-individual pattern in localization and progression …

[HTML][HTML] Analysis and validation of hub genes in neutrophil extracellular traps for the long-term prognosis of myocardial infarction

X Li, W Wu, H He, L Guan, G Chen, Z Lin, H Li, J Jiang… - Gene, 2024 - Elsevier
Introduction The study focuses on the long-term prognosis of myocardial infarction (MI)
influenced by neutrophil extracellular traps (NETs). It also aims to analyze and validate …

Associations of plaque morphology and location with Intraplaque neovascularization in the carotid artery by contrast-enhanced ultrasound imaging

SY Gu, LN Zhang, J Chen, F Li, MH Yao, CX Jia… - Frontiers in …, 2023 - frontiersin.org
Objective Intraplaque neovascularization (IPN) is a known indicator of plaque vulnerability,
and is thus considered a predictor of stroke. The morphology and location of the carotid …

Using computed tomography angiography and computational fluid dynamics to study aortic coarctation in different arch morphologies

J Qin, D Ouyang, T Yan, H Wang, K Guo, X **… - Frontiers in …, 2023 - frontiersin.org
Objective To study the differences in computed tomography angiography (CTA) imaging of
gothic arches, crenel arches, and romanesque arches in children with Aortic Coarctation …

[HTML][HTML] Influence of Aortic Valve Stenosis and Wall Shear Stress on Platelets Function

P Bańka, M Wybraniec, T Bochenek, B Gruchlik… - Journal of Clinical …, 2023 - mdpi.com
Aortic valve stenosis (AS) is a common heart valve disease in the elderly population, and its
pathogenesis remains an interesting area of research. The degeneration of the aortic valve …