Staphylococcus aureus host interactions and adaptation

BP Howden, SG Giulieri, T Wong Fok Lung… - Nature Reviews …, 2023 - nature.com
Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

KM Kennedy, MC de Goffau, ME Perez-Muñoz… - Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …

Emergence of methicillin resistance predates the clinical use of antibiotics

J Larsen, CL Raisen, X Ba, NJ Sadgrove… - Nature, 2022 - nature.com
The discovery of antibiotics more than 80 years ago has led to considerable improvements
in human and animal health. Although antibiotic resistance in environmental bacteria is …

Towards the biogeography of prokaryotic genes

LP Coelho, R Alves, ÁR Del Río, PN Myers… - Nature, 2022 - nature.com
Microbial genes encode the majority of the functional repertoire of life on earth. However,
despite increasing efforts in metagenomic sequencing of various habitats,–, little is known …

Diversity and pathogenesis of Staphylococcus aureus from bovine mastitis: current understanding and future perspectives

B Campos, AC Pickering, LS Rocha, AP Aguilar… - BMC Veterinary …, 2022 - Springer
Staphylococcus aureus is a leading cause of bovine mastitis worldwide. Despite some
improved understanding of disease pathogenesis, progress towards new methods for the …

Mobile genetic element flexibility as an underlying principle to bacterial evolution

AJ Weisberg, JH Chang - Annual Review of Microbiology, 2023 - annualreviews.org
Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …

Comparative genomics reveals insights into cyanobacterial evolution and habitat adaptation

MY Chen, WK Teng, L Zhao, CX Hu, YK Zhou… - The ISME …, 2021 - academic.oup.com
Cyanobacteria are photosynthetic prokaryotes that inhabit diverse aquatic and terrestrial
environments. However, the evolutionary mechanisms involved in the cyanobacterial habitat …

Evolutionary pathways and trajectories in antibiotic resistance

F Baquero, JL Martinez, V F. Lanza… - Clinical Microbiology …, 2021 - Am Soc Microbiol
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Staphylococcus aureus in Animals

AF Haag, JR Fitzgerald, JR Penadés - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a mammalian commensal and opportunistic pathogen that
colonizes niches such as skin, nares and diverse mucosal membranes of about 20-30% of …

Apparent nosocomial adaptation of Enterococcus faecalis predates the modern hospital era

AK Pöntinen, J Top, S Arredondo-Alonso… - Nature …, 2021 - nature.com
Enterococcus faecalis is a commensal and nosocomial pathogen, which is also ubiquitous
in animals and insects, representing a classical generalist microorganism. Here, we study E …