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Liquid phase partitioning in virus replication: observations and opportunities
Viruses frequently carry out replication in specialized compartments within cells. The effect
of these structures on virus replication is poorly understood. Recent research supports …
of these structures on virus replication is poorly understood. Recent research supports …
[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Structure of the Ebola virus polymerase complex
B Yuan, Q Peng, J Cheng, M Wang, J Zhong, J Qi… - Nature, 2022 - nature.com
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although
two therapeutic monoclonal antibodies have been approved to treat the Ebola virus …
two therapeutic monoclonal antibodies have been approved to treat the Ebola virus …
Ebola viral glycoprotein bound to its endosomal receptor Niemann-Pick C1
Summary Filoviruses, including Ebola and Marburg, cause fatal hemorrhagic fever in
humans and primates. Understanding how these viruses enter host cells could help to …
humans and primates. Understanding how these viruses enter host cells could help to …
Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …
outbreaks have been documented, the majority of which have occurred in Central Africa …
Structure and assembly of the Ebola virus nucleocapsid
W Wan, L Kolesnikova, M Clarke, A Koehler, T Noda… - Nature, 2017 - nature.com
Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex at 3.6 Å resolution
Ebola virus causes haemorrhagic fever with a high fatality rate in humans and non-human
primates. It belongs to the family Filoviridae in the order Mononegavirales, which are viruses …
primates. It belongs to the family Filoviridae in the order Mononegavirales, which are viruses …
Structural and functional aspects of Ebola virus proteins
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …
Assembly of the Ebola virus nucleoprotein from a chaperoned VP35 complex
Ebolavirus NP oligomerizes into helical filaments found at the core of the virion,
encapsidates the viral RNA genome, and serves as a scaffold for additional viral proteins …
encapsidates the viral RNA genome, and serves as a scaffold for additional viral proteins …
Molecular insights into the Ebola virus life cycle
Ebola virus and other orthoebolaviruses cause severe haemorrhagic fevers in humans, with
very high case fatality rates. Their non-segmented single-stranded RNA genome encodes …
very high case fatality rates. Their non-segmented single-stranded RNA genome encodes …