Liquid phase partitioning in virus replication: observations and opportunities

C Wu, AS Holehouse, DW Leung… - Annual review of …, 2022 - annualreviews.org
Viruses frequently carry out replication in specialized compartments within cells. The effect
of these structures on virus replication is poorly understood. Recent research supports …

[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat

M Rojas, DM Monsalve, Y Pacheco… - Journal of …, 2020 - Elsevier
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

Structure of the Ebola virus polymerase complex

B Yuan, Q Peng, J Cheng, M Wang, J Zhong, J Qi… - Nature, 2022 - nature.com
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although
two therapeutic monoclonal antibodies have been approved to treat the Ebola virus …

Ebola viral glycoprotein bound to its endosomal receptor Niemann-Pick C1

H Wang, Y Shi, J Song, J Qi, G Lu, J Yan, GF Gao - Cell, 2016 - cell.com
Summary Filoviruses, including Ebola and Marburg, cause fatal hemorrhagic fever in
humans and primates. Understanding how these viruses enter host cells could help to …

Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach

M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022 - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …

Structure and assembly of the Ebola virus nucleocapsid

W Wan, L Kolesnikova, M Clarke, A Koehler, T Noda… - Nature, 2017 - nature.com
Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …

Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex at 3.6 Å resolution

Y Sugita, H Matsunami, Y Kawaoka, T Noda, M Wolf - Nature, 2018 - nature.com
Ebola virus causes haemorrhagic fever with a high fatality rate in humans and non-human
primates. It belongs to the family Filoviridae in the order Mononegavirales, which are viruses …

Structural and functional aspects of Ebola virus proteins

S Jain, E Martynova, A Rizvanov, S Khaiboullina… - Pathogens, 2021 - mdpi.com
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …

Assembly of the Ebola virus nucleoprotein from a chaperoned VP35 complex

RN Kirchdoerfer, DM Abelson, S Li, MR Wood… - Cell reports, 2015 - cell.com
Ebolavirus NP oligomerizes into helical filaments found at the core of the virion,
encapsidates the viral RNA genome, and serves as a scaffold for additional viral proteins …

Molecular insights into the Ebola virus life cycle

BS Bodmer, T Hoenen, L Wendt - Nature Microbiology, 2024 - nature.com
Ebola virus and other orthoebolaviruses cause severe haemorrhagic fevers in humans, with
very high case fatality rates. Their non-segmented single-stranded RNA genome encodes …