Evolution, discovery, and interpretations of arthropod mushroom bodies

NJ Strausfeld, L Hansen, Y Li, RS Gomez… - Learning & …, 1998 - learnmem.cshlp.org
Mushroom bodies are prominent neuropils found in annelids and in all arthropod groups
except crustaceans. First explicitly identified in 1850, the mushroom bodies differ in size and …

What do the mushroom bodies do for the insect brain? An introduction

M Heisenberg - Learning & memory, 1998 - learnmem.cshlp.org
Despite public claims to the contrary, our functional understanding of the brain is still
rudimentary. Starting with FJ Gall's Phrenology of the late eighteenth century, one of the …

Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis

T Lee, L Luo - Neuron, 1999 - cell.com
We describe a genetic mosaic system in Drosophila, in which a dominant repressor of a cell
marker is placed in trans to a mutant gene of interest. Mitotic recombination events between …

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

MA Cowley, JL Smart, M Rubinstein, MG Cerdán… - Nature, 2001 - nature.com
The administration of leptin to leptin-deficient humans, and the analogous Lep ob/Lep ob
mice, effectively reduces hyperphagia and obesity,. But common obesity is associated with …

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

M **g, Y Li, J Zeng, P Huang, M Skirzewski, O Kljakic… - Nature …, 2020 - nature.com
The ability to directly measure acetylcholine (ACh) release is an essential step toward
understanding its physiological function. Here we optimized the GRABACh (GPCR …

Spatiotemporal Rescue of Memory Dysfunction in Drosophila

SE McGuire, PT Le, AJ Osborn, K Matsumoto, RL Davis - Science, 2003 - science.org
We have developed a method for temporal and regional gene expression targeting
(TARGET) in Drosophila and show the simultaneous spatial and temporal rescue of a …

[HTML][HTML] A systematic nomenclature for the insect brain

K Ito, K Shinomiya, M Ito, JD Armstrong, G Boyan… - Neuron, 2014 - cell.com
Despite the importance of the insect nervous system for functional and developmental
neuroscience, descriptions of insect brains have suffered from a lack of uniform …

Conditional modification of behavior in Drosophila by targeted expression of a temperature‐sensitive shibire allele in defined neurons

T Kitamoto - Journal of neurobiology, 2001 - Wiley Online Library
Behavior is a manifestation of temporally and spatially defined neuronal activities. To
understand how behavior is controlled by the nervous system, it is important to identify the …

The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells

K Ito, W Awano, K Suzuki, Y Hiromi… - …, 1997 - journals.biologists.com
The mushroom body (MB) is an important centre for higher order sensory integration and
learning in insects. To analyse the development and organisation of the MB neuropile in …

Development of the Drosophila mushroom bodies: sequential generation of three distinct types of neurons from a neuroblast

T Lee, A Lee, L Luo - Development, 1999 - journals.biologists.com
The mushroom bodies (MBs) are prominent structures in the Drosophila brain that are
essential for olfactory learning and memory. Characterization of the development and …