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[HTML][HTML] RONS and oxidative stress: an overview of basic concepts
Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …
Singlet oxygen, photodynamic therapy, and mechanisms of cancer cell death
Photodynamic therapy (PDT) can be developed into an important arsenal against cancer; it
is a minimally invasive therapy, which is used in the treatment or/and palliation of a variety of …
is a minimally invasive therapy, which is used in the treatment or/and palliation of a variety of …
[HTML][HTML] Catalase, a remarkable enzyme: targeting the oldest antioxidant enzyme to find a new cancer treatment approach
This review is centered on the antioxidant enzyme catalase and will present different
aspects of this particular protein. Among them: historical discovery, biological functions …
aspects of this particular protein. Among them: historical discovery, biological functions …
Cold atmospheric plasma, a novel promising anti-cancer treatment modality
Over the past decade, cold atmospheric plasma (CAP), a near room temperature ionized
gas has shown its promising application in cancer therapy. Two CAP devices, namely …
gas has shown its promising application in cancer therapy. Two CAP devices, namely …
[HTML][HTML] The multifaceted roles of NRF2 in Cancer: friend or foe?
C Glorieux, C Enríquez, C González… - Antioxidants, 2024 - mdpi.com
Physiological concentrations of reactive oxygen species (ROS) play vital roles in various
normal cellular processes, whereas excessive ROS generation is central to disease …
normal cellular processes, whereas excessive ROS generation is central to disease …
The peroxisome-mitochondria connection: how and why?
Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid
and reactive oxygen species metabolism. In mammals, these organelles have also been …
and reactive oxygen species metabolism. In mammals, these organelles have also been …
[HTML][HTML] Natural antioxidant evaluation: A review of detection methods
Antioxidants have drawn the attention of the scientific community due to being related to the
prevention of various degenerative diseases. The antioxidant capacity has been extensively …
prevention of various degenerative diseases. The antioxidant capacity has been extensively …
Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule
S Chriett, A Dąbek, M Wojtala, H Vidal, A Balcerczyk… - Scientific reports, 2019 - nature.com
Butyrate and R-β-hydroxybutyrate are two related short chain fatty acids naturally found in
mammals. Butyrate, produced by enteric butyric bacteria, is present at millimolar …
mammals. Butyrate, produced by enteric butyric bacteria, is present at millimolar …
ATF6 decreases myocardial ischemia/reperfusion damage and links ER stress and oxidative stress signaling pathways in the heart
Rationale: Endoplasmic reticulum (ER) stress causes the accumulation of misfolded proteins
in the ER, activating the transcription factor, ATF6 (activating transcription factor 6 alpha) …
in the ER, activating the transcription factor, ATF6 (activating transcription factor 6 alpha) …
ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron
S Lu, X Wang, C He, L Wang, S Liang… - Acta Pharmacologica …, 2021 - nature.com
Ferroptotic cell death is characterized by iron-dependent lipid peroxidation that is initiated by
ferrous iron and H2O2 via Fenton reaction, in which the role of activating transcription factor …
ferrous iron and H2O2 via Fenton reaction, in which the role of activating transcription factor …