Rapid advances in nanopore technologies for sequencing single long DNA and RNA
molecules have led to substantial improvements in accuracy, read length and throughput …

Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …

A long-held goal in sequencing has been to use a voltage-biased nanoscale pore in a
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …

DNA sequence represents a single format onto which a broad range of biological
phenomena can be projected for high-throughput data collection. Over the past three years …

We present single-molecule, real-time sequencing data obtained from a DNA polymerase
performing uninterrupted template-directed synthesis using four distinguishable …

A nanopore-based device provides single-molecule detection and analytical capabilities
that are achieved by electrophoretically driving molecules in solution through a nano-scale …

A single-molecule method for sequencing DNA that does not require fluorescent labelling
could reduce costs and increase sequencing speeds. An exonuclease enzyme might be …

Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

In nanopore analytics, individual molecules pass through a single nanopore giving rise to
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …

Means to analyse cellular proteins and their millions of variants at the single-molecule level
would uncover substantial information previously unknown to biology. Nanopore …