How have animals managed to maintain metabolically expensive brains given the volatile
and fleeting availability of calories in the natural world? Here we review studies in support of …

The dynamics, distribution and activity of subcellular organelles are integral to regulating
cell shape changes during various physiological processes such as epithelial cell formation …

During starvation, mammalian brains can adapt their metabolism, switching from glucose to
alternative peripheral fuel sources. In the Drosophila starved brain, memory formation is …

Monocarboxylate transporter 4 (MCT4) is an H+-coupled symporter highly expressed in
metastatic tumors and at inflammatory sites undergoing hypoxia or the Warburg effect. At …

Information processing is energetically expensive. In the mammalian brain, it is unclear how
information coding and energy use are regulated during food scarcity. Using whole-cell …

The fruit fly can evaluate its energy state and decide whether to pursue food-related cues.
Here, we reveal that the mushroom body (MB) integrates hunger and satiety signals to …

The organs and metabolic pathways involved in energy metabolism, and the process of ATP
production from nutrients, are comparable between humans and Drosophila melanogaster …

Astrocytic metabolism has taken center stage. Interposed between the neuron and the
vasculature, astrocytes exert control over the fluxes of energy and building blocks required …

Coordinated activity across networks of neurons is a hallmark of both resting and active
behavioural states in many species,,,–. These global patterns alter energy metabolism over …

The astronomical increase of the world's aged population is associated with the increased
prevalence of neurodegenerative diseases, heightened disability, and extremely high costs …