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Mode of action-based risk assessment of genotoxic carcinogens
A Hartwig, M Arand, B Epe, S Guth, G Jahnke… - Archives of …, 2020 - Springer
The risk assessment of chemical carcinogens is one major task in toxicology. Even though
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …
exposure has been mitigated effectively during the last decades, low levels of carcinogenic …
The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment
IMCM Rietjens, A Michael, HM Bolt, B Siméon… - Archives of …, 2022 - Springer
The “totality” of the human exposure is conceived to encompass life-associated endogenous
and exogenous aggregate exposures. Process-related contaminants (PRCs) are not only …
and exogenous aggregate exposures. Process-related contaminants (PRCs) are not only …
Biomonitoring for occupational health risk assessment (BOHRA)
M Manno, C Viau, J Cocker, C Colosio, L Lowry, A Mutti… - Toxicology letters, 2010 - Elsevier
Biological monitoring (BM or biomonitoring) deals with the assessment of individual human
exposure, effect and susceptibility to occupational risk factors. It is a fundamental tool in …
exposure, effect and susceptibility to occupational risk factors. It is a fundamental tool in …
[HTML][HTML] Hemoglobin adducts of acrylamide in human blood–What has been done and what is next?
Acrylamide forms in many commonly consumed foods. In animals, acrylamide causes
tumors, neurotoxicity, developmental and reproductive effects. Acrylamide crosses the …
tumors, neurotoxicity, developmental and reproductive effects. Acrylamide crosses the …
Mass spectrometry analysis of DNA and protein adducts as biomarkers in human exposure to cigarette smoking: acrolein as an example
HJC Chen - Chemical Research in Toxicology, 2023 - ACS Publications
Acrolein is a major component in cigarette smoke and a product of endogenous lipid
peroxidation. It is difficult to distinguish human exposure to acrolein from exogenous sources …
peroxidation. It is difficult to distinguish human exposure to acrolein from exogenous sources …
Analytical approaches for MCPD esters and glycidyl esters in food and biological samples: a review and future perspectives
C Crews, A Chiodini, M Granvogl… - Food Additives & …, 2013 - Taylor & Francis
Esters of 2-and 3-monochloropropane-1, 2-diol (MCPD) and glycidol esters are important
contaminants of processed edible oils used as foods or food ingredients. This review …
contaminants of processed edible oils used as foods or food ingredients. This review …
[КНИГА][B] Chemical Weapons Convention chemicals analysis: sample collection, preparation and analytical methods
M Mesilaakso - 2005 - books.google.com
Describes the procedures for collection of samples, sample preparation, and analysis of
CWC-related chemicals. It deals with analytical procedures that can be followed in well …
CWC-related chemicals. It deals with analytical procedures that can be followed in well …
Toward an “omic” physiopathology of reactive chemicals: Thirty years of mass spectrometric study of the protein adducts with endogenous and xenobiotic compounds
FM Rubino, M Pitton, D Di Fabio… - Mass spectrometry …, 2009 - Wiley Online Library
Cancer and degenerative diseases are major causes of morbidity and death, derived from
the permanent modification of key biopolymers such as DNA and regulatory proteins by …
the permanent modification of key biopolymers such as DNA and regulatory proteins by …
Sex difference in the non-linear relationship between ethylene oxide exposure and depressive symptoms: A cross-sectional study
S Jiang, Y Wang, M Wang, Y Xu, W Zhang… - Journal of Affective …, 2024 - Elsevier
Background Ethylene oxide (EO) has been recognized as an animal carcinogen and
environmental EO exposure was linked to several diseases. However, the association of EO …
environmental EO exposure was linked to several diseases. However, the association of EO …
New exposure biomarkers as tools for breast cancer epidemiology, biomonitoring, and prevention: a systematic approach based on animal evidence
RA Rudel, JM Ackerman, KR Attfield… - Environmental health …, 2014 - ehp.niehs.nih.gov
Background: Exposure to chemicals that cause rodent mammary gland tumors is common,
but few studies have evaluated potential breast cancer risks of these chemicals in humans …
but few studies have evaluated potential breast cancer risks of these chemicals in humans …