Synthetic cannabinoids: a pharmacological and toxicological overview

R Roque-Bravo, RS Silva, RF Malheiro… - Annual review of …, 2023 - annualreviews.org
Synthetic cannabinoids (SCs) are a chemically diverse group of new psychoactive
substances (NPSs) that target the endocannabinoid system, triggering a plethora of actions …

Cannabinoids in medicine: cancer, immunity, and microbial diseases

P Śledziński, A Nowak-Terpiłowska… - International journal of …, 2020 - mdpi.com
Recently, there has been a growing interest in the medical applications of Cannabis plants.
They owe their unique properties to a group of secondary metabolites known as …

The effects of cannabis use during pregnancy on low birth weight and preterm birth: a systematic review and meta-analysis

I Baía, RMSM Domingues - American Journal of Perinatology, 2022 - thieme-connect.com
Objective Our objective was to summarize the literature regarding the effects of cannabis
use during pregnancy on low birth weight (LBW), preterm birth (PTB), and small for …

Delta-9-tetrahydrocannabinol inhibits invasion of HTR8/SVneo human extravillous trophoblast cells and negatively impacts mitochondrial function

OLS Walker, H Gurm, R Sharma, N Verma, LL May… - Scientific reports, 2021 - nature.com
Prenatal cannabis use is a significant problem and poses important health risks for the
develo** fetus. The molecular mechanisms underlying these changes are not fully …

Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts

P Alves, C Amaral, N Teixeira, G Correia-da-Silva - Archives of toxicology, 2021 - Springer
Cannabidiol (CBD) is a constituent of Cannabis sativa without psychotropic activity, whose
medical benefits have been recognised. However, little is known about the potential toxic …

The impact of early life exposure to cannabis: The role of the endocannabinoid system

AA Martínez-Peña, GA Perono, SA Gritis… - International Journal of …, 2021 - mdpi.com
Cannabis use during pregnancy has continued to rise, particularly in developed countries,
as a result of the trend towards legalization and lack of consistent, evidence-based …

Rationalizing a prospective coupling effect of cannabinoids with the current pharmacotherapy for melanoma treatment

A Bachari, N Nassar, E Schanknecht… - WIREs Mechanisms …, 2024 - Wiley Online Library
Melanoma is one of the leading fatal forms of cancer, yet from a treatment perspective, we
have minimal control over its reoccurrence and resistance to current pharmacotherapies …

[HTML][HTML] Improving neurological and mental health outcomes for children with prenatal drug exposure

JL Oei - Seminars in Fetal and Neonatal Medicine, 2024 - Elsevier
Prenatal drug exposure is a global public health problem that will never be completely
eliminated. Some drugs are essential for maternal health but many others are used …

The endocannabinoids anandamide and 2-arachidonoylglycerol modulate the expression of angiogenic factors on HTR8/SVneo placental cells

J Maia, BM Fonseca, N Teixeira… - … and Essential Fatty Acids, 2022 - Elsevier
The interest on the endocannabinoid system (ECS) in human reproduction has grown due to
its involvement in placenta development, which led to growing concerns over pregnant …

Cannabinoids and the placenta: receptors, signaling and outcomes

ACE Rokeby, BV Natale, DRC Natale - Placenta, 2023 - Elsevier
Cannabis use during pregnancy is increasing. The improvement of pregnancy-related
symptoms including morning sickness and management of mood and stress are among the …