Objective. Technical advances in deep brain stimulation (DBS) are crucial to improve
therapeutic efficacy and battery life. We report the potentialities and pitfalls of one of the first …

The neuroscience of volition is an emerging subfield of the brain sciences, with hundreds of
papers on the role of consciousness in action formation published each year. This makes …

Background Abnormal beta band activity in the subthalamic nucleus (STN) is known to be
exaggerated in patients with Parkinson's disease, and the amplitude of such activity has …

Gait and balance abnormalities develop commonly in Parkinson's disease and are among
the motor symptoms most disabling and refractory to dopaminergic or other treatments …

Freezing of gait (FOG) is a sudden episodic inability to produce effective step** despite
the intention to walk. It typically occurs during gait initiation (GI) or modulation and may lead …

Gait disturbance is a common and severe symptom of Parkinson's disease that severely
impairs quality of life. Current treatments provide only partial benefits with wide variability in …

A brain-machine interface represents a promising therapeutic avenue for the treatment of
many neurologic conditions. Deep brain stimulation (DBS) is an invasive, neuro-modulatory …

Subthalamic nucleus (STN) deep brain stimulation (DBS) is an established therapy for
Parkinson's disease motor symptoms. The ideal site for implantation within STN, however …

The initiation of gait is a highly challenging task for the balance control system, and can be
used to investigate the neural control of upright posture maintenance during whole-body …

Abstract Analysis of coupling between the phases and amplitudes of neural oscillations has
gained increasing attention as an important mechanism for large-scale brain network …