Reactive oxygen species scavenging nanomedicine for the treatment of ischemic heart disease
Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …
Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies
P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …
life because of its associated complications, including diabetes, cardiovascular diseases …
The renin‐angiotensin‐aldosterone system in vascular inflammation and remodeling
The RAAS through its physiological effectors plays a key role in promoting and maintaining
inflammation. Inflammation is an important mechanism in the development and progression …
inflammation. Inflammation is an important mechanism in the development and progression …
Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans
HK Vincent, AG Taylor - International journal of obesity, 2006 - nature.com
Objective: Oxidative stress may be the unifying mechanism underlying the development of
comorbidities in obesity. Evidence suggests that a clustering of sources of oxidative stress …
comorbidities in obesity. Evidence suggests that a clustering of sources of oxidative stress …
NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities
Reactive oxygen species (ROS) influence many physiological processes including host
defense, hormone biosynthesis, fertilization, and cellular signaling. Increased ROS …
defense, hormone biosynthesis, fertilization, and cellular signaling. Increased ROS …
Renin-angiotensin system and cardiovascular risk
The renin-angiotensin system is a major regulatory system of cardiovascular and renal
function. Basic research has revealed exciting new aspects, which could lead to novel or …
function. Basic research has revealed exciting new aspects, which could lead to novel or …
Angiotensin II and inflammation: the effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockade
Abstract Angiotensin II (Ang II) increases adhesion molecules, cytokines and chemokines
and exerts a proinflammatory effect on leucocytes, endothelial cells and vascular smooth …
and exerts a proinflammatory effect on leucocytes, endothelial cells and vascular smooth …
Inflammatory lipid mediators in adipocyte function and obesity
Survival of multicellular organisms depends on their ability to fight infection, metabolize
nutrients, and store energy for times of need. Unsurprisingly, therefore, immunoregulatory …
nutrients, and store energy for times of need. Unsurprisingly, therefore, immunoregulatory …
Effect of postprandial hypertriglyceridemia and hyperglycemia on circulating adhesion molecules and oxidative stress generation and the possible role of simvastatin …
A Ceriello, L Quagliaro, L Piconi, R Assaloni… - Diabetes, 2004 - Am Diabetes Assoc
Adhesion molecules, particularly intracellular adhesion molecule (ICAM)-1, vascular cell
adhesion molecule (VCAM)-1, and E-selectin, have been associated with cardiovascular …
adhesion molecule (VCAM)-1, and E-selectin, have been associated with cardiovascular …
Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation
D Fliser, K Buchholz, H Haller - Circulation, 2004 - Am Heart Assoc
Background—Experimental studies revealed proinflammatory properties of angiotensin II.
We evaluated antiinflammatory effects of the angiotensin II subtype 1 receptor antagonist …
We evaluated antiinflammatory effects of the angiotensin II subtype 1 receptor antagonist …