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Contemporary approaches for amide bond formation
Amide bond construction has garnered significant interest in recent decades due to amides
being one of the most prevalent functional groups among bioactive molecules. Out of the …
being one of the most prevalent functional groups among bioactive molecules. Out of the …
Cyrene: a bio-based novel and sustainable solvent for organic synthesis
Dihydrolevoclucosenone (Cyrene is its market name) is a biomass-derived solvent that can
be produced in only two steps from biomass, while being biodegradable, non-mutagenic …
be produced in only two steps from biomass, while being biodegradable, non-mutagenic …
Biocatalytic amide bond formation
Amide bonds occur in over half of target compounds in medicinal chemistry patents, making
amide bond formation the most commonly performed reaction in the pharmaceutical …
amide bond formation the most commonly performed reaction in the pharmaceutical …
Role and recent advancements of ionic liquids in drug delivery systems
MK Shukla, H Tiwari, R Verma, WL Dong, S Azizov… - Pharmaceutics, 2023 - mdpi.com
Advancements in the fields of ionic liquids (ILs) broaden its applications not only in
traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids …
traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids …
Water: an underestimated solvent for amide bond-forming reactions
Construction of the amide/peptide bond is one of the most encountered transformations in
the pharmaceutical and chemical industries. Traditional protocols rely on the use of …
the pharmaceutical and chemical industries. Traditional protocols rely on the use of …
Cyrene: a bio-based solvent for the Mizoroki–Heck reaction of aryl iodides
The development of greener and more sustainable methods, as well as the adaptation of
already existing protocols to more environmentally friendly procedures, has become crucial …
already existing protocols to more environmentally friendly procedures, has become crucial …
[HTML][HTML] Poly (ADP-Ribose) Polymerase (PARP) Inhibitors for Cancer Therapy: Advances, Challenges, and Future Directions
Poly (ADP-ribose) polymerases (PARPs) are crucial nuclear proteins that play important
roles in various cellular processes, including DNA repair, gene transcription, and cell death …
roles in various cellular processes, including DNA repair, gene transcription, and cell death …
Sustainable valorisation of renewables through dialkyl carbonates and isopropenyl esters
This review showcases a thorough analysis of reactions and applications of the most
widespread linear and alkylene organic carbonates (DACs), dimethyl-, diethyl-, ethylene …
widespread linear and alkylene organic carbonates (DACs), dimethyl-, diethyl-, ethylene …
Reactive deep eutectic solvents for EDC-mediated amide synthesis
The sustainability of amide bond formation is an ever-present topic in the pharmaceutical
industry, as it represents the common motif in many clinically approved drugs. Despite many …
industry, as it represents the common motif in many clinically approved drugs. Despite many …
Perspectives from the 2022 Cohort of the American Chemical Society Summer School on Green Chemistry & Sustainable Energy
The field of chemistry is uniquely equipped to solve many current and impending global
challenges; however, minimizing potential negative impacts on the environment, society …
challenges; however, minimizing potential negative impacts on the environment, society …