Anatomical and physiological differences between children and adults relevant to traumatic brain injury and the implications for clinical assessment and care

AA Figaji - Frontiers in neurology, 2017 - frontiersin.org
General and central nervous system anatomy and physiology in children is different to that of
adults and this is relevant to traumatic brain injury (TBI) and spinal cord injury. The …

Regulation of the cerebral circulation: bedside assessment and clinical implications

J Donnelly, KP Budohoski, P Smielewski, M Czosnyka - Critical care, 2016 - Springer
Regulation of the cerebral circulation relies on the complex interplay between
cardiovascular, respiratory, and neural physiology. In health, these physiologic systems act …

Sympathetic control of the brain circulation: appreciating the complexities to better understand the controversy

P Brassard, MM Tymko, PN Ainslie - Autonomic Neuroscience, 2017 - Elsevier
Although the human cerebral circulation is richly innervated with sympathetic nerve fibers,
the role of sympathetic nerve activity (SNA) on the regulation of cerebral blood flow (CBF) …

The neurosurgical and acute care management of tuberculous meningitis: evidence and current practice

AA Figaji, AG Fieggen - Tuberculosis, 2010 - Elsevier
Tuberculous meningitis (TBM) is the most lethal form of tuberculosis; mortality is high and
survivors are often left neurologically disabled. Several factors contribute to this poor …

Brain tissue oxygen tension and its response to physiological manipulations: influence of distance from injury site in a swine model of traumatic brain injury

GWJ Hawryluk, N Phan, AR Ferguson… - Journal of …, 2016 - thejns.org
OBJECTIVE The optimal site for placement of tissue oxygen probes following traumatic brain
injury (TBI) remains unresolved. The authors used a previously described swine model of …

Pediatric and neonatal mechanical ventilation

PC Rimensberger, SM Schulzke, D Tingay… - From Basics to …, 2015 - Springer
Pediatric and neonatal mechanical ventilation 123 Pediatric and Neonatal Mechanical
Ventilation Peter C. Rimensberger Editor From Basics to Clinical Practice Page 2 Pediatric and …

Aspects on the physiological and biochemical foundations of neurocritical care

CH Nordström, LO Koskinen, M Olivecrona - Frontiers in neurology, 2017 - frontiersin.org
Neurocritical care (NCC) is a branch of intensive care medicine characterized by specific
physiological and biochemical monitoring techniques necessary for identifying cerebral …

Monitoring Oxygenation

C Adami - Veterinary Anesthesia and Analgesia: The Sixth …, 2024 - Wiley Online Library
The goal of physiologic monitoring during anesthesia is to ensure an adequate oxygen
supply to maintain mitochondrial aerobic metabolism and, ultimately, cellular function. This …

Low brain oxygenation and differences in neuropsychological outcomes following severe pediatric TBI

LE Schrieff-Elson, KGF Thomas, UK Rohlwink… - Child's nervous …, 2015 - Springer
Purpose Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in children.
Preventing secondary injury by controlling physiological parameters (eg intracranial …

Pathophysiology and treatment of severe traumatic brain injuries in children

KA Allen - Journal of neuroscience nursing, 2016 - journals.lww.com
Traumatic brain injuries (TBIs) in children are a major cause of morbidity and mortality
worldwide. Severe TBIs account for 15,000 admissions annually and a mortality rate of 24 …