Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

In this short review, we give an overview of microtubule nucleation within cells. It is nearly 30
years since the discovery of γ-tubulin, a member of the tubulin superfamily essential for …

The cell orchestrates the dance of chromosome segregation with remarkable speed and
fidelity. The mitotic spindle is built from scratch after interphase through microtubule (MT) …

Microtubules (MTs) are highly conserved polar polymers that are key elements of the
eukaryotic cytoskeleton and are essential for various cell functions. αβ-tubulin, a …

Organisms with closed or open mitosis have differentially evolved various gamma-tubulin
complex (γ-TuC) recruiting factors to organize diverse cellular microtubule (MT) arrays …

Microtubule organization depends on the γ-tubulin ring complex (γ-TuRC), a∼ 2.3-MDa
nucleation factor comprising an asymmetric assembly of γ-tubulin and GCP2-GCP6 …

The microtubule nucleator γ-tubulin ring complex (γTuRC) is essential for the function of
microtubule organizing centers such as the centrosome. Since its discovery over two …

Non-centrosomal microtubule organizing centers (ncMTOCs) are found in most
differentiated cells, but how these structures regulate microtubule organization and …

Regulation of the γ-tubulin ring complex (γTuRC) through targeting and activation restricts
nucleation of microtubules to microtubule-organizing centers (MTOCs), aiding in the …

Centrosomes are a functionally conserved feature of eukaryotic cells that play an important
role in cell division. The conserved γ-tubulin complex organizes spindle and astral …