The immunogenetics of Behçet's disease: A comprehensive review

M Takeuchi, DL Kastner, EF Remmers - Journal of autoimmunity, 2015 - Elsevier
Behçet's disease is a chronic multisystem inflammatory disorder characterized mainly by
recurrent oral ulcers, ocular involvement, genital ulcers, and skin lesions, presenting with …

Behçet's disease

V Kontogiannis, RJ Powell - Postgraduate medical journal, 2000 - academic.oup.com
Behçet's disease is a systemic vasculitis of unknown aetiology characteristically affecting
venules. Onset is typically in young adults with recurrent oral and genital ulceration, uveitis …

[PDF][PDF] Behcet's disease: an update on the pathogenesis

A Gul - Clinical and experimental rheumatology, 2001 - clinexprheumatol.org
Behçet's disease is a chronic inflammatory disorder of unknown etiology. It has long been
postulated that immunological abnormalities, which are possibly induced by microbial …

Identification of a susceptibility locus in STAT4 for Behçet's disease in Han Chinese in a genome‐wide association study

S Hou, Z Yang, L Du, Z Jiang, Q Shu… - Arthritis & …, 2012 - Wiley Online Library
Objective To identify susceptibility loci for Behçet's disease (BD) and elucidate their
functional role. Methods A genome‐wide association study (GWAS) and functional studies …

Behcet disease-associated MHC class I residues implicate antigen binding and regulation of cell-mediated cytotoxicity

MJ Ombrello, Y Kirino, PIW de Bakker… - Proceedings of the …, 2014 - National Acad Sciences
The HLA protein, HLA-B* 51, encoded by HLA-B in MHC, is the strongest known genetic risk
factor for Behçet disease (BD). Associations between BD and other factors within the MHC …

Genetics of Behçet disease inside and outside the MHC

A Meguro, H Inoko, M Ota, Y Katsuyama… - Annals of the …, 2010 - ard.bmj.com
Background Behçet disease (BD) is a rare, chronic, systemic, inflammatory disorder
characterised by recurrent ocular, genital and skin lesions. Although its aetiology is still …

HLA-B* 51 and Behçet disease

A Gul, S Ohno - Ocular immunology and inflammation, 2012 - Taylor & Francis
Behçet disease (BD) is a multisystem inflammatory disorder of unknown etiology. BD has a
multifactorial pathogenesis, and genetics plays a critical role in the development of the …

Association analysis between the MIC‐A and HLA–B alleles in Japanese patients with Behçet's disease

N Mizuki, M Ota, Y Katsuyama, K Yabuki… - … : Official Journal of …, 1999 - Wiley Online Library
Objective Behçet's disease is known to be strongly associated with HLA–B51 in many
different ethnic groups. Recently, by association analysis using refined microsatellite …

A plausible contributor to multiple sclerosis; presentation of antigenic myelin protein epitopes by major histocompatibility complexes

S Jakhmola, MF Sk, A Chatterjee, K Jain, P Kar… - Computers in Biology …, 2022 - Elsevier
Background Multiple sclerosis (MS) can be induced upon successful presentation of myelin
antigens by MHC I/II. Antigenic similarity between the myelin and viral proteins may worsen …

Immune‐mediated inflammatory diseases of the gastrointestinal tract: Beyond Crohn's disease and ulcerative colitis

SK Vuyyuru, S Kedia, P Sahu, V Ahuja - JGH Open, 2022 - Wiley Online Library
Immune‐mediated inflammatory diseases (IMIDs) are a diverse group of complex
inflammatory diseases that result from dysregulated immune pathways and can involve any …