[HTML][HTML] Polyoxovanadates with emerging biomedical activities

M Aureliano, NI Gumerova, G Sciortino… - Coordination Chemistry …, 2021 - Elsevier
Polyoxovanadates (POVs) are a subclass of a larger family of polyanionic group V and VI
metal-oxo clusters that are known as polyoxometalates (POMs). POMs have been found to …

[HTML][HTML] Polyoxidovanadates' interactions with proteins: An overview

M Aureliano, NI Gumerova, G Sciortino… - Coordination Chemistry …, 2022 - Elsevier
Polyoxidovanadates (POVs, previously named polyoxovanadates) are a subgroup of
polyoxidometalates (POMs, previously named polyoxometalates) with interesting …

Polyoxometalates as potential next‐generation metallodrugs in the combat against cancer

A Bijelic, M Aureliano, A Rompel - … Chemie International Edition, 2019 - Wiley Online Library
Polyoxometalates (POMs) are an emerging class of inorganic metal oxides, which over the
last decades demonstrated promising biological activities by the virtue of their great diversity …

ATP and adenosine metabolism in cancer: exploitation for therapeutic gain

GG Yegutkin, D Boison, S Alexander - Pharmacological reviews, 2022 - Elsevier
Adenosine is an evolutionary ancient metabolic regulator linking energy state to physiologic
processes, including immunomodulation and cell proliferation. Tumors create an adenosine …

[HTML][HTML] Adenosine metabolism: emerging concepts for cancer therapy

D Boison, GG Yegutkin - Cancer cell, 2019 - cell.com
Adenosine is a key metabolic and immune-checkpoint regulator implicated in the tumor
escape from the host immune system. Major gaps in knowledge that impede the …

Medicinal chemistry of adenosine, P2Y and P2X receptors

KA Jacobson, CE Müller - Neuropharmacology, 2016 - Elsevier
Pharmacological tool compounds are now available to define action at the adenosine (ARs),
P2Y and P2X receptors. We present a selection of the most commonly used agents to study …

All‐Inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers

A Barba‐Bon, NI Gumerova, E Tanuhadi… - Advanced …, 2024 - Wiley Online Library
Polyoxometalates (POMs) are known antitumoral, antibacterial, antiviral, and anticancer
agents and considered as next‐generation metallodrugs. Herein, a new biological …

Polyoxometalates in biomedicine: Update and overview

MB Čolović, M Lacković, J Lalatović… - Current medicinal …, 2020 - ingentaconnect.com
Background: Polyoxometalates (POMs) are negatively charged metal-oxo clusters of early
transition metal ions in high oxidation states (eg, WVI, MoVI, VV). POMs are of interest in the …

[HTML][HTML] CD39–A bright target for cancer immunotherapy

S Guo, F Han, W Zhu - Biomedicine & Pharmacotherapy, 2022 - Elsevier
The ATP-adenosine pathway functions as a key modulator of innate and adaptive immunity
within the tumor microenvironment, and cancer immune evasion largely involves the …

The future of polyoxymetalates for biological and chemical apllications

MJW Budych, K Staszak, A Bajek, F Pniewski… - Coordination Chemistry …, 2023 - Elsevier
This paper reports the most interesting applications of polyoxometalates (POMs) over the
last five years, highlighting the relationship between their complex nature, properties, and …