Methods for handling multiple testing

TK Rice, NJ Schork, DC Rao - Advances in genetics, 2008 - Elsevier
The availability of high‐throughput genoty** technologies and massive amounts of marker
data for testing genetic associations is a dual‐edged sword. On one side is the possibility …

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

OA Andreassen, S Djurovic, WK Thompson… - The American Journal of …, 2013 - cell.com
Several lines of evidence suggest that genome-wide association studies (GWASs) have the
potential to explain more of the" missing heritability" of common complex phenotypes …

Randomization inference in the regression discontinuity design: An application to party advantages in the US Senate

MD Cattaneo, BR Frandsen, R Titiunik - Journal of Causal Inference, 2015 - degruyter.com
Abstract In the Regression Discontinuity (RD) design, units are assigned a treatment based
on whether their value of an observed covariate is above or below a fixed cutoff. Under the …

All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs

AJ Schork, WK Thompson, P Pham, A Torkamani… - PLoS …, 2013 - journals.plos.org
Recent results indicate that genome-wide association studies (GWAS) have the potential to
explain much of the heritability of common complex phenotypes, but methods are lacking to …

Federated learning for intrusion detection in IoT security: a hybrid ensemble approach

S Chatterjee, MK Hanawal - … of Internet of Things and Cyber …, 2022 - inderscienceonline.com
Critical role of the internet of things (IoT) in various domains like smart city, healthcare,
supply chain, and transportation has made them the target of malicious attacks. Past works …

Stratified false discovery control for large‐scale hypothesis testing with application to genome‐wide association studies

L Sun, RV Craiu, AD Paterson… - … : The Official Publication …, 2006 - Wiley Online Library
The multiplicity problem has become increasingly important in genetic studies as the
capacity for high-throughput genoty** has increased. The control of False Discovery Rate …

Explainable Deep Contrastive Federated Learning System for Early Prediction of Clinical Status in-Intensive Care Unit

TN Nguyen, HJ Yang, BG Kho, SR Kang… - IEEE Access, 2024 - ieeexplore.ieee.org
Early identification of patients' clinical status plays a critical role in intensive care unit (ICU)
care. The increased adoption of electronic health records (EHRs) in the ICU creates …

[HTML][HTML] Gene–environment interaction: Oxytocin receptor (OXTR) polymorphisms and parenting style as potential predictors for depressive symptoms

R Keijser, C Åslund, KW Nilsson, S Olofsdotter - Psychiatry Research, 2021 - Elsevier
Depression is a common mental health problem that is thought to develop through a
combination of genetic, psychological, and environmental factors, including parental …

Bias-corrected estimators for proportion of true null hypotheses: application of adaptive FDR-controlling in segmented failure data

A Biswas, G Chattopadhyay… - Journal of Applied …, 2022 - Taylor & Francis
Two recently introduced model-based bias-corrected estimators for proportion of true null
hypotheses (π 0) under multiple hypotheses testing scenario have been restructured for …

Inconsistency of findings due to low power: A structural MRI study of bilingualism

BA Munson, AE Hernandez - Brain and language, 2019 - Elsevier
Research on structural brain differences between monolinguals and bilinguals remains
inconsistent, and this has been proposed by some to be due in part to inadequate sample …