A review on chitosan-based biomaterial as carrier in tissue engineering and medical applications

L Wang, Z Xu, H Zhang, C Yao - European Polymer Journal, 2023 - Elsevier
Recently, chitosan-based biomaterials as carriers are favored by tissue and medical
engineering researchers for their excellent physical, chemical and biological properties in …

[HTML][HTML] Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells

R Augustine, P Dan, A Hasan, IM Khalaf… - Biomedicine & …, 2021 - Elsevier
Cardiovascular disease is one of the leading causes of mortality worldwide. Cardiac tissue
engineering strategies focusing on biomaterial scaffolds incorporating cells and growth …

Thermoresponsive mixed polymer brush to effectively control the adhesion and separation of stem cells by altering temperature

K Nagase, H Wakayama, J Matsuda, N Kojima… - Materials Today Bio, 2023 - Elsevier
During the last few decades, thermoresponsive materials for modulating cell adhesion have
been investigated for the application of tissue engineering. In this study, we developed …

Optimization of a PDMS-based cell culture substrate for high-density human-induced pluripotent stem cell adhesion and long-term differentiation into cardiomyocytes …

F Etezadi, MNT Le, H Shahsavarani… - ACS biomaterials …, 2022 - ACS Publications
Despite the numerous advantages of PDMS-based substrates in various biomedical
applications, they are limited by their highly hydrophobic surface that does not optimally …

[HTML][HTML] Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes

J Afzal, Y Liu, W Du, Y Suhail, P Zong, J Feng, V Ajeti… - Cell reports, 2022 - cell.com
The vast potential of human induced pluripotent stem-cell-derived cardiomyocytes (hiPSC-
CMs) in preclinical models of cardiac pathologies, precision medicine, and drug screening …

Hydration and dehydration behaviors of poly (N-isopropylacrylamide)-grafted silica beads

K Nagase, J Matsuda, A Takeuchi, Y Ikemoto - Surfaces and Interfaces, 2023 - Elsevier
The use of poly (N-isopropyl acrylamide)(PNIPAAm) in thermoresponsive interfaces for
biomedical applications has been extensively investigated. Understanding the hydration …

Multitunable LCST and UCST behaviors of Y-junction-bearing polyacrylamides

Y Lin, L Lian, J Hu, M Zhang, Y Zhao - Macromolecules, 2023 - ACS Publications
Rational design of thermoresponsive polymers allows facile control over LCST/UCST and
nano-object shapes. Despite tremendous progress, it remains a challenge to monitor chain …

Thermoresponsive block copolymer brush for temperature-modulated hepatocyte separation

K Nagase, N Kojima, M Goto, T Akaike… - Journal of Materials …, 2022 - pubs.rsc.org
Hepatic tissue engineering may be an effective approach for the treatment of liver disease;
however, its practical application requires hepatic cell separation technologies that do not …

The tissue engineering revolution: from bench research to clinical reality

F De Chiara, A Ferret-Miñana, JM Fernández-Costa… - Biomedicines, 2024 - mdpi.com
At its core, tissue engineering involves the use of a scaffold for the formation of new viable
tissue for medical purposes. This field has expanded to include the development of …

[HTML][HTML] Surface properties and bioactivity of PNIPAM-grafted-chitosan/chondroitin multilayers

YT Lu, PT Hung, K Zeng, C Woelk, B Fuhrmann… - Smart Materials in …, 2023 - Elsevier
The thermoresponsive poly (N-isopropylacrylamide)(PNIPAM) is widely applied in the
biomedical field particularly as thermoresponsive substrate for culture of cells. To be used as …