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Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines
Background The objective of this study was to summarize the published literature
concerning the epidemiology of lung cancer. Methods A narrative review of published …
concerning the epidemiology of lung cancer. Methods A narrative review of published …
Epidemiology of lung cancer: looking to the future
In the United States, the 20th century witnessed the emergence of a lung cancer epidemic
that peaked and began to decline by the century's end, a decline that continues today …
that peaked and began to decline by the century's end, a decline that continues today …
[ספר][B] DNA repair and mutagenesis
An essential resource for all scientists researching cellular responses to DNA damage.•
Introduces important new material reflective of the major changes and developments that …
Introduces important new material reflective of the major changes and developments that …
ERCC2 /XPD Gene Polymorphisms and Lung Cancer: A HuGE Review
The xeroderma pigmentosum group D (XPD) protein is a well-characterized DNA helicase
necessary for the nucleotide excision repair of bulky DNA lesions, such as those induced by …
necessary for the nucleotide excision repair of bulky DNA lesions, such as those induced by …
Specific combinations of DNA repair gene variants and increased risk for non-small cell lung cancer
O Popanda, T Schattenberg, CT Phong… - …, 2004 - academic.oup.com
Several polymorphisms in DNA repair genes have been reported to be associated with lung
cancer risk including XPA (− 4G/A), XPD (Lys751Gln and Asp312Asn), XRCC1 (Arg399Gln) …
cancer risk including XPA (− 4G/A), XPD (Lys751Gln and Asp312Asn), XRCC1 (Arg399Gln) …
Polymorphisms in XPC, XPD, XRCC1, and XRCC3 DNA repair genes and lung cancer risk in a population of Northern Spain
M Felicitas López-Cima, P González-Arriaga… - BMC cancer, 2007 - Springer
Background Polymorphisms in DNA repair genes have been associated to repair DNA
lesions, and might contribute to the individual susceptibility to develop different types of …
lesions, and might contribute to the individual susceptibility to develop different types of …
Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis
C Kiyohara, K Yoshimasu - International journal of medical …, 2007 - pmc.ncbi.nlm.nih.gov
Various DNA alterations can be caused by exposure to environmental and endogenous
carcinogens. Most of these alterations, if not repaired, can result in genetic instability …
carcinogens. Most of these alterations, if not repaired, can result in genetic instability …
Polymorphisms in DNA Base Excision Repair Genes ADPRT and XRCC1 and Risk of Lung Cancer
Adenosine diphosphate ribosyl transferase (ADPRT) and X-ray repair cross-complementing
1 (XRCC1) are two major DNA base excision repair (BER) proteins and act interactively in …
1 (XRCC1) are two major DNA base excision repair (BER) proteins and act interactively in …
Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk
DNA repair function is believed to play an important role in cancer development and to be
affected by genetic polymorphisms. Numerous epidemiological studies have examined the …
affected by genetic polymorphisms. Numerous epidemiological studies have examined the …
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer
The tumor suppressor TP53 pathway plays a crucial role in preventing carcinogenesis
through its ability to impose cell cycle arrest and apoptosis following DNA damage and …
through its ability to impose cell cycle arrest and apoptosis following DNA damage and …