Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium)-induced hepatotoxicity–A review
Heavy metals pose a serious threat if they go beyond permissible limits in our bodies. Much
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …
Mitochondria as the target of hepatotoxicity and drug-induced liver injury: molecular mechanisms and detection methods
M Mihajlovic, M Vinken - International journal of molecular sciences, 2022 - mdpi.com
One of the major mechanisms of drug-induced liver injury includes mitochondrial
perturbation and dysfunction. This is not a surprise, given that mitochondria are essential …
perturbation and dysfunction. This is not a surprise, given that mitochondria are essential …
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury
F Lin, W Chen, J Zhou, J Zhu, Q Yao, B Feng… - Cell death & …, 2022 - nature.com
Mesenchymal stem cells (MSCs) have attracted interest for their potential to alleviate liver
injury. Here, the protective effect of MSCs on carbon tetrachloride (CCl4)-induced acute liver …
injury. Here, the protective effect of MSCs on carbon tetrachloride (CCl4)-induced acute liver …
Hepatoprotective Effect of Apigenin Against Liver Injury via the Non-canonical NF-κB Pathway In Vivo and In Vitro
S Yue, N Xue, H Li, B Huang, Z Chen, X Wang - Inflammation, 2020 - Springer
Apigenin, a flavonoid found in many plants, has various biological properties. We aimed to
investigate the anti-inflammatory and anti-oxidative activity of apigenin against carbon …
investigate the anti-inflammatory and anti-oxidative activity of apigenin against carbon …
Docetaxel and lidocaine co-loaded (NLC-in-hydrogel) hybrid system designed for the treatment of melanoma
Melanoma is the most aggressive skin carcinoma and nanotechnology can bring new
options for its pharmacological treatment. Nanostructured lipid carriers (NLC) are ideal drug …
options for its pharmacological treatment. Nanostructured lipid carriers (NLC) are ideal drug …
Binary polymeric amorphous carvedilol solid dispersions: In vitro and in vivo characterization
M Krstić, L Manić, N Martić, D Vasiljević… - European Journal of …, 2020 - Elsevier
Binary polymeric amorphous carvedilol solid dispersions were prepared using solvent
method by varying solvent type, polymer type and carvedilol to polymer ratio in order to …
method by varying solvent type, polymer type and carvedilol to polymer ratio in order to …
Antioxidative and protective actions of apigenin in a paracetamol-induced hepatotoxicity rat model
A Rašković, S Gigov, I Čapo, M Paut Kusturica… - European Journal of …, 2017 - Springer
Abstract Background and Objectives Apigenin is known to have various pharmacological
properties without causing significant toxicity; however, hepatoprotective effect of apigenin is …
properties without causing significant toxicity; however, hepatoprotective effect of apigenin is …
Formulation and biopharmaceutical evaluation of supersaturatable self-nanoemulsifying drug delivery systems containing silymarin
The first objective of this study was to optimize a supersaturatable self-nanoemulsifying drug
delivery system (S-SNEDDS) containing silymarin through the investigation of the single and …
delivery system (S-SNEDDS) containing silymarin through the investigation of the single and …
Devices and techniques used to obtain and analyze three‐dimensional cell cultures
G Agrawal, A Ramesh, P Aishwarya… - Biotechnology …, 2021 - Wiley Online Library
Cell cultures are indispensable for both basic and applied research. Advancements in cell
culture and analysis increase their utility for basic research and translational applications. A …
culture and analysis increase their utility for basic research and translational applications. A …
Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
Arachidonic acid (AA) signaling pathway is an important constituent of inflammatory
processes. In our previous study, it was found that dihydro-stilbene gigantol relieved hepatic …
processes. In our previous study, it was found that dihydro-stilbene gigantol relieved hepatic …