Depression—an underrecognized target for prevention of dementia in Alzheimer's disease

FS Dafsari, F Jessen - Translational psychiatry, 2020 - nature.com
It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be
modifiable by the management of risk factors. While several recent guidelines and …

Assessment and management of behavioral and psychological symptoms of dementia

HC Kales, LN Gitlin, CG Lyketsos - Bmj, 2015 - bmj.com
Behavioral and psychological symptoms of dementia include agitation, depression, apathy,
repetitive questioning, psychosis, aggression, sleep problems, wandering, and a variety of …

Depression as a microglial disease

R Yirmiya, N Rimmerman, R Reshef - Trends in neurosciences, 2015 - cell.com
Despite decades of intensive research, the biological mechanisms that causally underlie
depression are still unclear, and therefore the development of novel effective antidepressant …

[HTML][HTML] Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms

KL Lanctôt, J Amatniek, S Ancoli-Israel… - Alzheimer's & Dementia …, 2017 - Elsevier
Neuropsychiatric symptoms (NPSs) are hallmarks of Alzheimer's disease (AD), causing
substantial distress for both people with dementia and their caregivers, and contributing to …

Best practice in the management of behavioural and psychological symptoms of dementia

OP Tible, F Riese, E Savaskan… - Therapeutic advances …, 2017 - journals.sagepub.com
Behavioural and psychological symptoms of dementia (BPSD) occur in most patients with
dementia. They cause great suffering in patients and caregivers, sometimes more so than …

Depression and risk of develo** dementia

AL Byers, K Yaffe - Nature Reviews Neurology, 2011 - nature.com
Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …

Management of neuropsychiatric symptoms of dementia in clinical settings: recommendations from a multidisciplinary expert panel

HC Kales, LN Gitlin, CG Lyketsos… - Journal of the …, 2014 - Wiley Online Library
Noncognitive neuropsychiatric symptoms (NPS) of dementia (aggression, agitation,
depression, anxiety, delusions, hallucinations, apathy, disinhibition) affect individuals with …

Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis

JA Watt, Z Goodarzi, AA Veroniki, V Nincic, PA Khan… - bmj, 2021 - bmj.com
Objective To describe the comparative efficacy of drug and non-drug interventions for
reducing symptoms of depression in people with dementia who experience depression as a …

Depression in Alzheimer's disease: epidemiology, mechanisms, and treatment

YY Huang, YH Gan, L Yang, W Cheng, JT Yu - Biological Psychiatry, 2024 - Elsevier
Depression and Alzheimer's disease (AD) are substantial public health concerns. In the past
decades, a link between the 2 disease entities has received extensive acknowledgment, yet …

Mood disorders in the medically ill: scientific review and recommendations

DL Evans, DS Charney, L Lewis, RN Golden… - Biological …, 2005 - Elsevier
OBJECTIVE: The purpose of this review is to assess the relationship between mood
disorders and development, course, and associated morbidity and mortality of selected …