Pharmacology and therapeutics of bronchodilators revisited

MG Matera, CP Page, L Calzetta, P Rogliani… - Pharmacological …, 2020 - Elsevier
Bronchodilators remain the cornerstone of the treatment of airway disorders such as asthma
and chronic obstructive pulmonary disease (COPD). There is therefore considerable interest …

Asthma endoty** and biomarkers in childhood asthma

A Licari, R Castagnoli, I Brambilla… - Pediatric allergy …, 2018 - liebertpub.com
Childhood asthma represents a heterogeneous challenging disease, in particular in its
severe forms. The identification of different asthma phenotypes has stimulated research in …

Omics technologies in allergy and asthma research: An EAACI position paper

U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …

[HTML][HTML] Asthma heterogeneity and severity

TF Carr, E Bleecker - World Allergy Organization Journal, 2016 - Elsevier
Asthma is a common, chronic inflammatory airways disease characterized by a clinical
syndrome of bronchial hyperresponsiveness, inflammation, and reversible airflow …

The predictive role of biomarkers and genetics in childhood asthma exacerbations

E di Palmo, E Cantarelli, A Catelli, G Ricci… - International journal of …, 2021 - mdpi.com
Asthma exacerbations are associated with significant childhood morbidity and mortality.
Recurrent asthma attacks contribute to progressive loss of lung function and can sometimes …

Pharmacogenetic factors affecting asthma treatment response. potential implications for drug therapy

JM García-Menaya, C Cordobés-Durán… - Frontiers in …, 2019 - frontiersin.org
Asthma is a frequent disease, mainly characterized by airway inflammation, in which drug
therapy is crucial in its management. The potential of pharmacogenomics testing in asthma …

[HTML][HTML] Receptor Pharmacogenomics: Deciphering Genetic Influence on Drug Response

SA Anghel, CE Dinu-Pirvu, MA Costache… - International Journal of …, 2024 - mdpi.com
The paradigm “one drug fits all” or “one dose fits all” will soon be challenged by
pharmacogenetics research and application. Drug response—efficacy or safety—depends …

Omics for the future in asthma

MI Abdel-Aziz, AH Neerincx, SJ Vijverberg… - Seminars in …, 2020 - Springer
Asthma is a common, complex, multifaceted disease. It comprises multiple phenotypes,
which might benefit from treatment with different types of innovative targeted therapies …

Colony‐stimulating factor 1 and its receptor are new potential therapeutic targets for allergic asthma

HG Moon, S Kim, MK Lee, H Kang, HS Choi, A Harijith… - Allergy, 2020 - Wiley Online Library
Background A new approach targeting aeroallergen sensing in the early events of mucosal
immunity could have greater benefit. The CSF1‐CSF1R pathway has a critical role in …

Asthma exacerbation prediction: recent insights

L Fleming - Current opinion in allergy and clinical immunology, 2018 - journals.lww.com
Asthma exacerbation prediction: recent insights : Current Opinion in Allergy and Clinical
Immunology Asthma exacerbation prediction: recent insights : Current Opinion in Allergy and …