Hyperandrogenemia and insulin resistance: The chief culprit of polycystic ovary syndrome
J Wang, D Wu, H Guo, M Li - Life sciences, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is one of the most common systemic reproductive
endocrine diseases, which has a variety of effects on a woman's health. Because of the …
endocrine diseases, which has a variety of effects on a woman's health. Because of the …
Adipocyte and steroidogenic cell cross-talk in polycystic ovary syndrome
BACKGROUND Metabolic and endocrine alterations in women with polycystic ovary
syndrome (PCOS) affect adipose tissue mass and distribution. PCOS is characterised by …
syndrome (PCOS) affect adipose tissue mass and distribution. PCOS is characterised by …
Mechanisms of adiponectin action in fertility: an overview from gametogenesis to gestation in humans and animal models in normal and pathological conditions
Adiponectin is the most abundant plasma adipokine. It mainly derives from white adipose
tissue and plays a key role in the control of energy metabolism thanks to its insulin …
tissue and plays a key role in the control of energy metabolism thanks to its insulin …
The complex roles of adipokines in polycystic ovary syndrome and endometriosis
S Schüler-Toprak, O Ortmann, C Buechler, O Treeck - Biomedicines, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) and endometriosis are frequent diseases of the female
reproductive tract causing high morbidity as they can significantly affect fertility and quality of …
reproductive tract causing high morbidity as they can significantly affect fertility and quality of …
Adipose tissue and reproductive health
H Mathew, VD Castracane, C Mantzoros - Metabolism, 2018 - Elsevier
The understanding of adipose tissue role has evolved from that of a depot energy storage
organ to a dynamic endocrine organ. While genetics, sexual phenotype and sex steroids …
organ to a dynamic endocrine organ. While genetics, sexual phenotype and sex steroids …
The effect of excess body fat on female and male reproduction
The dramatic increase in the prevalence of obesity coincides with a decline in reproductive
health indices in both sexes. Energy excess mediates changes to the regulatory …
health indices in both sexes. Energy excess mediates changes to the regulatory …
Adiponectin and resistin: potential metabolic signals affecting hypothalamo-pituitary gonadal axis in females and males of different species
Adipokines, including adiponectin and resistin, are cytokines produced mainly by the
adipose tissue. They play a significant role in metabolic functions that regulate the insulin …
adipose tissue. They play a significant role in metabolic functions that regulate the insulin …
Ovarian expression of adipokines in polycystic ovary syndrome: a role for chemerin, omentin, and apelin in follicular growth arrest and ovulatory dysfunction?
A Bongrani, N Mellouk, C Rame, M Cornuau… - International journal of …, 2019 - mdpi.com
Adipokines are a potential link between reproduction and energy metabolism and could
partly explain some infertilities related to some pathophysiology, such as polycystic ovary …
partly explain some infertilities related to some pathophysiology, such as polycystic ovary …
Adipocytokines: are they the theory of everything?
PS Maximus, Z Al Achkar, PF Hamid, SS Hasnain… - Cytokine, 2020 - Elsevier
Introduction Adipose tissue secretes various bioactive peptides/proteins, immune molecules
and inflammatory mediators which are known as adipokines or adipocytokines. Adipokines …
and inflammatory mediators which are known as adipokines or adipocytokines. Adipokines …
Ovarian and extra-ovarian mediators in the development of polycystic ovary syndrome
M Puttabyatappa… - Journal of molecular …, 2018 - jme.bioscientifica.com
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder affecting women
of reproductive age. The origin of PCOS is still not clear and appears to be a function of …
of reproductive age. The origin of PCOS is still not clear and appears to be a function of …