Biomaterial-based platforms for tumour tissue engineering

R Curvello, V Kast, P Ordóñez-Morán, A Mata… - Nature Reviews …, 2023 - nature.com
Tissue engineering has produced innovative tools for cancer research. 3D cancer models
based on molecularly designed biomaterials aim to harness the dimensionality and …

Advances, challenges, and future directions in the clinical translation of ECM biomaterials for regenerative medicine applications

H Capella-Monsonís, RJ Crum, GS Hussey… - Advanced Drug Delivery …, 2024 - Elsevier
Extracellular Matrix (ECM) scaffolds and biomaterials have been widely used for decades
across a variety of diverse clinical applications and have been implanted in millions of …

Breaking the stromal barrier in pancreatic cancer: Advances and challenges

M Chakkera, JB Foote, B Farran… - Biochimica et Biophysica …, 2024 - Elsevier
Pancreatic cancer (PC) remains a leading cause of mortality worldwide due to the absence
of early detection methods and the low success rates of traditional therapeutic strategies …

Biofabrication and monitoring of a 3D printed skin model for melanoma

P Vázquez‐Aristizabal… - Advanced …, 2024 - Wiley Online Library
There is an unmet need for in vitro cancer models that emulate the complexity of human
tissues. 3D‐printed solid tumor micromodels based on decellularized extracellular matrices …

[HTML][HTML] In vitro veritas: from 2D cultures to organ-on-a-chip models to study immunogenic cell death in the tumor microenvironment

DV Krysko, R Demuynck, I Efimova, F Naessens… - Cells, 2022 - mdpi.com
Immunogenic cell death (ICD) is a functionally unique form of cell death that promotes a T-
cell-dependent anti-tumor immune response specific to antigens originating from dying …

The occurrence and development mechanisms of esophageal stricture: state of the art review

F Yang, Y Hu, Z Shi, M Liu, K Hu, G Ye, Q Pang… - Journal of translational …, 2024 - Springer
Background Esophageal strictures significantly impair patient quality of life and present a
therapeutic challenge, particularly due to the high recurrence post-ESD/EMR. Current …

A decellularized lung extracellular matrix/chondroitin sulfate/gelatin/chitosan-based 3D culture system shapes breast cancer lung metastasis

L Wang, J Yang, X Hu, S Wang, Y Wang, T Sun… - Biomaterials …, 2023 - Elsevier
Distal metastasis of breast cancer is a primary cause of death, and the lung is a common
metastatic target of breast cancer. However, the role of the lung niche in promoting breast …

Three-dimensional printing and decellularized-extracellular-matrix based methods for advances in artificial blood vessel fabrication: a review

B Li, Y Shu, H Ma, K Cao, YY Cheng, Z Jia, X Ma… - Tissue and Cell, 2024 - Elsevier
Blood vessels are the tubes through which blood flows and are divided into three types:
millimeter-scale arteries, veins, and capillaries as well as micrometer-scale capillaries …

Recent advances in micro-physiological systems for investigating tumor metastasis and organotropism

H Yoon, JS Del Río, SW Cho, TE Park - Lab on a Chip, 2024 - pubs.rsc.org
Tumor metastasis involves complex processes that traditional 2D cultures and animal
models struggle to fully replicate. Metastatic tumors undergo a multitude of transformations …

Nerve decellularized matrix composite scaffold with high antibacterial activity for nerve regeneration

Y Kong, D Wang, Q Wei, Y Yang - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Nerve decellularized matrix (NDM) has received much attention due to its natural
composition and structural advantages that had proven to be an excellent candidate for …