Cardiovascular impact of androgen deprivation therapy: from basic biology to clinical practice

J Kim, K Freeman, A Ayala, MK Mullen, Z Sun… - Current Oncology …, 2023 - Springer
Abstract Purpose of the Review There have been increasing reports of cardiovascular
complications of androgen deprivation therapy (ADT) leading to worse outcomes among …

Prostate cancer treatment and the relationship of androgen deprivation therapy to cognitive function

AB Reiss, U Saeedullah, DJ Grossfeld… - Clinical and …, 2022 - Springer
Prostate cancer is the second most common form of cancer in men. For advanced, high risk
prostate cancer, androgen deprivation therapy (ADT) is the preferred treatment and can …

Knockout of NRF2 triggers prostate cancer cells death through ROS modulation and sensitizes to cisplatin

MCS Mancini, AP Morelli, MB Severino… - Journal of Cellular …, 2022 - Wiley Online Library
Prostate cancer (PCa) represents the second most common cancer in men and affects
millions worldwide. Chemotherapy is a common treatment for PCa but the development of …

Development and evaluation of a PSMA-targeted nanosystem co-packaging docetaxel and androgen receptor siRNA for castration-resistant prostate cancer treatment

Y Zhang, H Duan, H Zhao, L Qi, Y Liu, Z Zhang, C Liu… - Pharmaceutics, 2022 - mdpi.com
Primary prostate cancer (PC) progresses to castration-resistant PC (CRPC) during androgen
deprivation therapy (ADR) in early stages of prostate cancer. Thus, rather than blocking the …

[HTML][HTML] Comparative cardiovascular safety of gonadotropin-releasing hormone antagonists and agonists among patients diagnosed with prostate cancer: a …

S Patel, K Zhu, CV Dave, M Ghajar, Y Zhang… - European Urology …, 2024 - Elsevier
Background and objective Gonadotropin-releasing hormone (GnRH) antagonists and
agonists are cornerstone treatments in prostate cancer. However, evidence regarding the …

Androgen deprivation therapy in high-risk localized and locally advanced prostate cancer

H Iwamoto, K Izumi, T Makino, A Mizokami - Cancers, 2022 - mdpi.com
Simple Summary Androgen deprivation therapy alone is commonly performed for metastatic
prostate cancer but is generally not recommended for the treatment of high-risk localized or …

Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection

M Weingartner, S Stücheli, F Jebbawi… - PLoS neglected …, 2022 - journals.plos.org
Background Echinococcus multilocularis causes alveolar echinococcosis (AE), a rising
zoonotic disease in the northern hemisphere. Treatment of this fatal disease is limited to …

Cardiometabolic side effects of androgen deprivation therapy in prostate cancer

ML Lafontaine, A Kokorovic - Current Opinion in Supportive and …, 2022 - journals.lww.com
Cardiometabolic side effects of androgen deprivation therapy... : Current Opinion in Supportive
and Palliative Care Cardiometabolic side effects of androgen deprivation therapy in prostate …

Multi-institutional analysis of the clinical and genomic characteristics of black patients with metastatic hormone-sensitive prostate cancer

MN Freeman, A Jang, J Zhu, F Sanati… - The …, 2022 - academic.oup.com
Background The outcomes of metastatic hormone-sensitive prostate cancer (mHSPC) have
significantly improved through treatment intensification, yet Black representation in those …

Lapatinib antitumor effect is associated with PI3K and MAPK pathway: An analysis in human and canine prostate cancer cells

CE Fonseca-Alves, AF Leis-Filho, ZA Lacerda… - Plos one, 2024 - journals.plos.org
The aberrant activation of HER2 has a pivotal role in bone metastasis implantation and
progression in several tumor types, including prostate cancer (PC). Trastuzumab and other …