Engineering the next generation of cell-based therapeutics
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …
intractable diseases through uniquely powerful modes of action. Despite notable recent …
Stimuli‐responsive nanocomposite hydrogels for biomedical applications
The complex tissue‐specific physiology that is orchestrated from the nano‐to the
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …
Deep brain stimulation by blood–brain-barrier-crossing piezoelectric nanoparticles generating current and nitric oxide under focused ultrasound
Deep brain stimulation via implanted electrodes can alleviate neuronal disorders. However,
its applicability is constrained by side effects resulting from the insertion of electrodes into …
its applicability is constrained by side effects resulting from the insertion of electrodes into …
Tether-free photothermal deep-brain stimulation in freely behaving mice via wide-field illumination in the near-infrared-II window
Neural circuitry is typically modulated via invasive brain implants and tethered optical fibres
in restrained animals. Here we show that wide-field illumination in the second near-infrared …
in restrained animals. Here we show that wide-field illumination in the second near-infrared …
Prussian blue nanozyme as a pyroptosis inhibitor alleviates neurodegeneration
X Ma, J Hao, J Wu, Y Li, X Cai, Y Zheng - Advanced Materials, 2022 - Wiley Online Library
Current pharmacological interventions for Parkinson's disease (PD) remain unsatisfactory in
clinical settings. Inflammasome‐mediated pyroptosis represents a potential therapeutic …
clinical settings. Inflammasome‐mediated pyroptosis represents a potential therapeutic …
Mucosa-interfacing electronics
The surface mucosa that lines many of our organs houses myriad biometric signals and,
therefore, has great potential as a sensor–tissue interface for high-fidelity and long-term …
therefore, has great potential as a sensor–tissue interface for high-fidelity and long-term …
Wireless and battery-free technologies for neuroengineering
Tethered and battery-powered devices that interface with neural tissues can restrict natural
motions and prevent social interactions in animal models, thereby limiting the utility of these …
motions and prevent social interactions in animal models, thereby limiting the utility of these …
Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics
Optogenetics has revolutionized the experimental interrogation of neural circuits and holds
promise for the treatment of neurological disorders. It is limited, however, because visible …
promise for the treatment of neurological disorders. It is limited, however, because visible …
Self-rectifying magnetoelectric metamaterials for remote neural stimulation and motor function restoration
Magnetoelectric materials convert magnetic fields into electric fields. These materials are
often used in wireless electronic and biomedical applications. For example …
often used in wireless electronic and biomedical applications. For example …
Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …