Cancer is the second leading cause of death in the world and one of the major public health
problems. Despite the great advances in cancer therapy, the incidence and mortality rates of …

Tumour metastasis, the movement of tumour cells from a primary site to progressively
colonize distant organs, is a major contributor to the deaths of cancer patients. Therapeutic …

Men who develop metastatic castration-resistant prostate cancer (CRPC) invariably
succumb to the disease. Progression to CRPC after androgen ablation therapy is …

Cancer is a life-threatening disease and is the second leading cause of death around the
world. The increasing threats of drug-resistant cancers indicate that there is an urgent need …

While the antiandrogen enzalutamide (Enz) extends the castration resistant prostate cancer
(CRPC) patients' survival an extra 4.8 months, it might also result in some adverse effects via …

Elevated levels of chemokine CC motif ligand 2 (CCL2) and its receptor CCR2 have been
reported in patients with temporal lobe epilepsy and in experimental seizures. However, the …

Curcumin (diferuloylmethane) is the main constituent extracted from turmeric. This
polyphenol is a non-toxic, potent compound with anticancer, anti-inflammatory, antibacterial …

Acne, the most common skin disease, is a disorder of pilosebaceous units that affects
adolescents mainly and adults occasionally. The pathogenesis is multifactorial. Besides …

Prostate cancer (PC), the second most prevalent malignancy in men worldwide, has been
proven to depend on the aberrant activation of androgen receptor (AR) signaling. Long-term …

Medullary thyroid carcinomas (MTC) arise from thyroid parafollicular, calcitonin-producing C-
cells and can occur either as sporadic or as hereditary diseases in the context of familial …