Magnetic resonance imaging and spectroscopic techniques are widely used in humans both
for clinical diagnostic applications and in basic research areas such as cognitive …

AGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium
chelates. This nanoparticle has been recently accepted in clinical trials in association with …

Cancer, being one of the deadliest diseases, poses significant challenges despite the
existence of traditional treatment approaches. This has led to a growing demand for …

Glioblastoma multiforme (GBM) is the most aggressive malignant brain tumor. Despite new
knowledges on the genetic characteristics, conventional therapy for GBM, tumor resection …

Gliomas are highly lethal tumours characterised by heterogeneous molecular features,
producing various metabolic phenotypes leading to therapeutic resistance. Lipid metabolism …

We report a convenient strategy to prepare ultrasmall Fe3O4 nanoparticles (NPs) coated
with zwitterion L-cysteine (Cys) for enhanced T1-weighted magnetic resonance (MR) …

Nanomedicine in oncology has not had the success in clinical impact that was anticipated in
the early stages of the field's development. Ideally, nanomedicines selectively accumulate in …

Intratumoral injection of chemotherapy agents may be employed in the treatment of cancers.
However, its anti-tumor efficacy is significantly impeded by collagen fibers in the tumor which …

Despite combined treatments, glioblastoma outcome remains poor with frequent local
recurrences, indicating that a more efficient and local therapy is needed. In this way …

Glioblastoma (GBM) is the most difficult brain cancer to treat, and photodynamic therapy
(PDT) is emerging as a complementary approach to improve tumor eradication. Neuropilin-1 …