A paradigm shift in imaging biomarkers in neovascular age-related macular degeneration
U Schmidt-Erfurth, SM Waldstein - Progress in Retinal and eye Research, 2016 - Elsevier
Neovascular age-related macular degeneration (AMD) has undergone substantial break-
throughs in diagnostic as well as therapeutic respect, with optical coherence tomography …
throughs in diagnostic as well as therapeutic respect, with optical coherence tomography …
A view of the current and future role of optical coherence tomography in the management of age-related macular degeneration
U Schmidt-Erfurth, S Klimscha, SM Waldstein… - Eye, 2017 - nature.com
Optical coherence tomography (OCT) has become an established diagnostic technology in
the clinical management of age-related macular degeneration (AMD). OCT is being used for …
the clinical management of age-related macular degeneration (AMD). OCT is being used for …
[HTML][HTML] Machine learning to analyze the prognostic value of current imaging biomarkers in neovascular age-related macular degeneration
Purpose To evaluate the potential of machine learning to predict best-corrected visual acuity
(BCVA) outcomes from structural and functional assessments during the initiation phase in …
(BCVA) outcomes from structural and functional assessments during the initiation phase in …
Prediction of anti-VEGF treatment requirements in neovascular AMD using a machine learning approach
Purpose: The purpose of this study was to predict low and high anti-VEGF injection
requirements during a pro re nata (PRN) treatment, based on sets of optical coherence …
requirements during a pro re nata (PRN) treatment, based on sets of optical coherence …
Morphology and visual acuity in aflibercept and ranibizumab therapy for neovascular age-related macular degeneration in the VIEW trials
Purpose To compare the efficacy of intravitreal aflibercept and ranibizumab on the exudative
activity of neovascular age-related macular degeneration (nAMD) using optical coherence …
activity of neovascular age-related macular degeneration (nAMD) using optical coherence …
[HTML][HTML] Machine learning of the progression of intermediate age-related macular degeneration based on OCT imaging
Purpose: To develop a data-driven interpretable predictive model of incoming drusen
regression as a sign of disease activity and identify optical coherence tomography (OCT) …
regression as a sign of disease activity and identify optical coherence tomography (OCT) …
Expert-level automated biomarker identification in optical coherence tomography scans
In ophthalmology, retinal biological markers, or biomarkers, play a critical role in the
management of chronic eye conditions and in the development of new therapeutics. While …
management of chronic eye conditions and in the development of new therapeutics. While …
Predicting macular edema recurrence from spatio-temporal signatures in optical coherence tomography images
Prediction of treatment responses from available data is key to optimizing personalized
treatment. Retinal diseases are treated over long periods and patients' response patterns …
treatment. Retinal diseases are treated over long periods and patients' response patterns …
[HTML][HTML] Analyzing and predicting visual acuity outcomes of anti-VEGF therapy by a longitudinal mixed effects model of imaging and clinical data
Purpose: We develop a longitudinal statistical model describing best-corrected visual acuity
(BCVA) changes in anti-VEGF therapy in relation to imaging data, and predict the future …
(BCVA) changes in anti-VEGF therapy in relation to imaging data, and predict the future …
Multivendor spectral‐domain optical coherence tomography dataset, observer annotation performance evaluation, and standardized evaluation framework for …
J Wu, AM Philip, D Podkowinski… - Journal of …, 2016 - Wiley Online Library
Development of image analysis and machine learning methods for segmentation of clinically
significant pathology in retinal spectral‐domain optical coherence tomography (SD‐OCT) …
significant pathology in retinal spectral‐domain optical coherence tomography (SD‐OCT) …